2022
Radiotracers to Address Unmet Clinical Needs in Cardiovascular Imaging, Part 2: Inflammation, Fibrosis, Thrombosis, Calcification, and Amyloidosis Imaging
Stendahl JC, Kwan JM, Pucar D, Sadeghi MM. Radiotracers to Address Unmet Clinical Needs in Cardiovascular Imaging, Part 2: Inflammation, Fibrosis, Thrombosis, Calcification, and Amyloidosis Imaging. Journal Of Nuclear Medicine 2022, 63: 986-994. PMID: 35772956, PMCID: PMC9258561, DOI: 10.2967/jnumed.121.263507.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsAmyloidosisCalcinosisFibrinFibrosisHumansInflammationPositron-Emission TomographyThrombosisConceptsCardiovascular imagingDevice-related thrombusDetection of thrombusUnmet diagnostic needsFibroblast activation proteinCardiovascular fibrosisCardiovascular inflammationRisk stratificationDiagnostic needsCardiovascular calcificationMyocardial infarctionInflammatory responseUnmet ClinicalNew radiotracersCardiovascular medicinePersonalized therapyFibrosisActivation proteinSPECT imagingAmyloidosisCalcificationThrombosisInflammationRadiotracer developmentThrombusRadiotracers to Address Unmet Clinical Needs in Cardiovascular Imaging, Part 1: Technical Considerations and Perfusion and Neuronal Imaging.
Stendahl JC, Kwan JM, Pucar D, Sadeghi MM. Radiotracers to Address Unmet Clinical Needs in Cardiovascular Imaging, Part 1: Technical Considerations and Perfusion and Neuronal Imaging. Journal Of Nuclear Medicine 2022, 63: 649-658. PMID: 35487563, DOI: 10.2967/jnumed.121.263506.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsAtherosclerosisHumansPerfusionPositron-Emission TomographyRadiopharmaceuticalsTomography, Emission-Computed, Single-PhotonConceptsUnmet diagnostic needsCardiovascular medicineNeuronal imagingImaging of inflammationHeart failureValvular diseaseTechnical considerationsDiagnostic needsCardiac amyloidosisUnmet ClinicalNew radiotracersCardiovascular imagingPersonalized therapyPerfusion tracerPET perfusion tracerThrombosisRadiotracer developmentRadiotracerPerfusionF-FlurpiridazImagingReviewMedicineKey technical considerationsMolecular characterization
2020
Prototype device for endoventricular beta-emitting radiotracer detection and molecularly-guided intervention
Stendahl JC, Liu Z, Boutagy NE, Nataneli E, Daghighian F, Sinusas AJ. Prototype device for endoventricular beta-emitting radiotracer detection and molecularly-guided intervention. Journal Of Nuclear Cardiology 2020, 29: 663-676. PMID: 32820423, PMCID: PMC7895860, DOI: 10.1007/s12350-020-02317-8.Peer-Reviewed Original Research11C-acetate PET: A powerful tool to analyze metabolic and functional changes in the heart related to alcohol consumption
Stendahl JC, Sinusas AJ. 11C-acetate PET: A powerful tool to analyze metabolic and functional changes in the heart related to alcohol consumption. Journal Of Nuclear Cardiology 2020, 29: 289-292. PMID: 32676907, PMCID: PMC7854759, DOI: 10.1007/s12350-020-02268-0.Commentaries, Editorials and LettersMeSH KeywordsAcetatesAlcohol DrinkingHeartHumansOxygen ConsumptionPositron-Emission TomographyTomography, X-Ray ComputedFeasibility study of PET dynamic imaging of [18F]DHMT for quantification of reactive oxygen species in the myocardium of large animals
Wu J, Boutagy NE, Cai Z, Lin SF, Zheng MQ, Feher A, Stendahl JC, Kapinos M, Gallezot JD, Liu H, Mulnix T, Zhang W, Lindemann M, Teng JK, Miller EJ, Huang Y, Carson RE, Sinusas AJ, Liu C. Feasibility study of PET dynamic imaging of [18F]DHMT for quantification of reactive oxygen species in the myocardium of large animals. Journal Of Nuclear Cardiology 2020, 29: 216-225. PMID: 32415628, PMCID: PMC7666654, DOI: 10.1007/s12350-020-02184-3.Peer-Reviewed Original ResearchAnimalsDogsFeasibility StudiesHumansMyocardiumPositron-Emission TomographyReactive Oxygen SpeciesSuperoxides
2016
Optimized and Automated Radiosynthesis of [18F]DHMT for Translational Imaging of Reactive Oxygen Species with Positron Emission Tomography
Zhang W, Cai Z, Li L, Ropchan J, Lim K, Boutagy NE, Wu J, Stendahl JC, Chu W, Gropler R, Sinusas AJ, Liu C, Huang Y. Optimized and Automated Radiosynthesis of [18F]DHMT for Translational Imaging of Reactive Oxygen Species with Positron Emission Tomography. Molecules 2016, 21: 1696. PMID: 27941676, PMCID: PMC5505691, DOI: 10.3390/molecules21121696.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsDogsFluorine RadioisotopesPositron-Emission TomographyRadiopharmaceuticalsTranslational Research, Biomedical
2015
Nanoparticles for Cardiovascular Imaging and Therapeutic Delivery, Part 2: Radiolabeled Probes
Stendahl JC, Sinusas AJ. Nanoparticles for Cardiovascular Imaging and Therapeutic Delivery, Part 2: Radiolabeled Probes. Journal Of Nuclear Medicine 2015, 56: 1637-1641. PMID: 26294304, PMCID: PMC4934892, DOI: 10.2967/jnumed.115.164145.BooksConceptsSmall molecule agentsTherapeutic deliveryNanoparticlesMolecular imagingDistinct propertiesTherapeutic applicationsFurther technologic developmentsTheranosticsAddress safety concernsProbeFunctional versatilitySignificant potentialAgentsClinical translationVersatilityPropertiesApplicationsPreclinical cardiovascular researchCurrent examples