2001
An Effective AIDS Vaccine Based on Live Attenuated Vesicular Stomatitis Virus Recombinants
Rose N, Marx P, Luckay A, Nixon D, Moretto W, Donahoe S, Montefiori D, Roberts A, Buonocore L, Rose J. An Effective AIDS Vaccine Based on Live Attenuated Vesicular Stomatitis Virus Recombinants. Cell 2001, 106: 539-549. PMID: 11551502, DOI: 10.1016/s0092-8674(01)00482-2.Peer-Reviewed Original ResearchMeSH KeywordsAcquired Immunodeficiency SyndromeAIDS VaccinesAnimalsCD4 Lymphocyte CountCD4-Positive T-LymphocytesEnzyme-Linked Immunosorbent AssayGene Products, envGene Products, gagHIVHIV AntibodiesHumansImmunization, SecondaryMacaca mulattaMiceNeutralization TestsPilot ProjectsRecombinant Fusion ProteinsSAIDS VaccinesSimian Acquired Immunodeficiency SyndromeSimian immunodeficiency virusTime FactorsT-Lymphocytes, CytotoxicVaccines, AttenuatedVaccines, SyntheticVesicular stomatitis Indiana virusViral LoadVirus Shedding
2000
Glycoprotein Exchange Vectors Based on Vesicular Stomatitis Virus Allow Effective Boosting and Generation of Neutralizing Antibodies to a Primary Isolate of Human Immunodeficiency Virus Type 1
Rose N, Roberts A, Buonocore L, Rose J. Glycoprotein Exchange Vectors Based on Vesicular Stomatitis Virus Allow Effective Boosting and Generation of Neutralizing Antibodies to a Primary Isolate of Human Immunodeficiency Virus Type 1. Journal Of Virology 2000, 74: 10903-10910. PMID: 11069984, PMCID: PMC113169, DOI: 10.1128/jvi.74.23.10903-10910.2000.Peer-Reviewed Original ResearchConceptsRecombinant VSV vectorVesicular stomatitis virusNeutralizing antibodiesPrimary isolatesVSV vectorsHigh-titer neutralizing antibodiesHuman immunodeficiency virus type 1Human immunodeficiency virus envelope proteinImmunodeficiency virus type 1HIV primary isolatesCross-neutralizing antibodiesRecombinant vesicular stomatitis virusVirus type 1Effective vaccine vectorAntibody titersWild-type vesicular stomatitis virusHIV envelopeForeign antigensImmune responseVirus envelope proteinVSV Indiana serotypeVaccine vectorType 1AntibodiesG protein gene
1999
Attenuated Vesicular Stomatitis Viruses as Vaccine Vectors
Roberts A, Buonocore L, Price R, Forman J, Rose J. Attenuated Vesicular Stomatitis Viruses as Vaccine Vectors. Journal Of Virology 1999, 73: 3723-3732. PMID: 10196265, PMCID: PMC104148, DOI: 10.1128/jvi.73.5.3723-3732.1999.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCattleCell LineCricetinaeFemaleGene ExpressionGenetic VectorsHemagglutinin Glycoproteins, Influenza VirusInfluenza VaccinesMembrane GlycoproteinsMiceMice, Inbred BALB COrthomyxoviridae InfectionsRecombination, GeneticTime FactorsVaccines, AttenuatedVaccines, SyntheticVesicular stomatitis Indiana virusViral Envelope ProteinsVirionConceptsVesicular stomatitis virusLethal influenza virus challengeComplete protectionInfluenza virus challengeRecombinant vesicular stomatitis virusSingle intranasal vaccinationInfluenza virus HAStomatitis virusIntranasal vaccinationLethal challengeIntranasal administrationVirus challengeMouse modelVaccine vectorVSV vectorsVirus HAInfluenza virusHemagglutinin proteinInfluenza virus hemagglutinin (HA) proteinG proteinsPathogenesisVirus hemagglutinin proteinVirusPresent studyVaccination