2008
VSV/MVA vaccine rapidly elicits SIV antibodies and local and systemic SIV T cell responses in macaque neonates but does not prevent SIV dissemination after oral challenge
Abel K, Van Rompay K, Eastlick J, Moore J, Lemieux M, Schmidt K, Earl P, Buonocore-Buzzelli L, Moss B, Rose N, Rose J, McChesney M, Kozlowski P, Marthas M. VSV/MVA vaccine rapidly elicits SIV antibodies and local and systemic SIV T cell responses in macaque neonates but does not prevent SIV dissemination after oral challenge. Retrovirology 2008, 5: o15. DOI: 10.1186/1742-4690-5-s1-o15.Peer-Reviewed Original Research
2001
Replication-Competent or Attenuated, Nonpropagating Vesicular Stomatitis Viruses Expressing Respiratory Syncytial Virus (RSV) Antigens Protect Mice against RSV Challenge
Kahn J, Roberts A, Weibel C, Buonocore L, Rose J. Replication-Competent or Attenuated, Nonpropagating Vesicular Stomatitis Viruses Expressing Respiratory Syncytial Virus (RSV) Antigens Protect Mice against RSV Challenge. Journal Of Virology 2001, 75: 11079-11087. PMID: 11602747, PMCID: PMC114687, DOI: 10.1128/jvi.75.22.11079-11087.2001.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, IntranasalAnimalsAntigens, ViralBase SequenceCell LineCricetinaeFemaleMiceMice, Inbred BALB CMolecular Sequence DataRespiratory Syncytial Virus InfectionsVaccines, AttenuatedVaccines, SyntheticVesicular stomatitis Indiana virusViral ProteinsViral VaccinesVirus ReplicationConceptsRespiratory syncytial virusRSV challengeRecombinant vesicular stomatitis virusVesicular stomatitis virusRSV FRespiratory syncytial virus GRSV-specific antibodiesDetectable neutralizing antibodiesDetectable serum antibodiesStomatitis virusIntranasal vaccinationRSV vaccineRSV GProtective immunitySyncytial virusDetectable serumNeutralizing antibodiesSerum antibodiesMouse modelRSV proteinsComplete protectionReplication competentAntibodiesG glycoproteinVirus
2000
Glycoprotein Exchange Vectors Based on Vesicular Stomatitis Virus Allow Effective Boosting and Generation of Neutralizing Antibodies to a Primary Isolate of Human Immunodeficiency Virus Type 1
Rose N, Roberts A, Buonocore L, Rose J. Glycoprotein Exchange Vectors Based on Vesicular Stomatitis Virus Allow Effective Boosting and Generation of Neutralizing Antibodies to a Primary Isolate of Human Immunodeficiency Virus Type 1. Journal Of Virology 2000, 74: 10903-10910. PMID: 11069984, PMCID: PMC113169, DOI: 10.1128/jvi.74.23.10903-10910.2000.Peer-Reviewed Original ResearchConceptsRecombinant VSV vectorVesicular stomatitis virusNeutralizing antibodiesPrimary isolatesVSV vectorsHigh-titer neutralizing antibodiesHuman immunodeficiency virus type 1Human immunodeficiency virus envelope proteinImmunodeficiency virus type 1HIV primary isolatesCross-neutralizing antibodiesRecombinant vesicular stomatitis virusVirus type 1Effective vaccine vectorAntibody titersWild-type vesicular stomatitis virusHIV envelopeForeign antigensImmune responseVirus envelope proteinVSV Indiana serotypeVaccine vectorType 1AntibodiesG protein genePresence of bovine viral diarrhea virus (BVDV) E2 glycoprotein in VSV recombinant particles and induction of neutralizing BVDV antibodies in mice
Grigera P, Marzocca M, Capozzo A, Buonocore L, Donis R, Rose J. Presence of bovine viral diarrhea virus (BVDV) E2 glycoprotein in VSV recombinant particles and induction of neutralizing BVDV antibodies in mice. Virus Research 2000, 69: 3-15. PMID: 10989181, DOI: 10.1016/s0168-1702(00)00164-7.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsAntibodies, ViralBase SequenceCattleCell LineChimeraCricetinaeDiarrhea Viruses, Bovine ViralDNA, RecombinantFemaleMembrane GlycoproteinsMiceMice, Inbred BALB CNeutralization TestsRecombinant ProteinsVaccines, SyntheticVesicular stomatitis Indiana virusViral Envelope ProteinsViral VaccinesConceptsBovine viral diarrhea virus (BVDV) E2BALB/c miceRecombinant vesicular stomatitis virusViral-induced diseasesC miceE2 antibodiesBVDV antibodiesVesicular stomatitis virusHigh avidityBVDV E2Recombinant E2Infected cellsDays post inoculationG glycoproteinE2Stomatitis virusMiceAntibodiesImmunofluorescence microscopyPost inoculationRecombinant particlesBHK21 cellsCellsSymptomsInfectionSuccessful Vaccine-Induced Seroconversion by Single-Dose Immunization in the Presence of Measles Virus-Specific Maternal Antibodies
Schlereth B, Rose J, Buonocore L, Meulen V, Niewiesk S. Successful Vaccine-Induced Seroconversion by Single-Dose Immunization in the Presence of Measles Virus-Specific Maternal Antibodies. Journal Of Virology 2000, 74: 4652-4657. PMID: 10775601, PMCID: PMC111985, DOI: 10.1128/jvi.74.10.4652-4657.2000.Peer-Reviewed Original ResearchConceptsMV-specific antibodiesMaternal antibodiesVesicular stomatitis virusMV hemagglutininVaccine-induced seroconversionCotton rat modelRecombinant vesicular stomatitis virusSingle-dose immunizationInduction of antibodiesSuccessful immunizationVirus doseRat modelSuccessful vaccineRat antibodiesSubsequent challengeMeasles virusDissociation of functionHigh titersImmunizationAntibodiesSeroconversionStomatitis virusInductionVirusHemagglutininSuccessful Vaccine-Induced Seroconversion by Single-Dose Immunization in the Presence of Measles Virus-Specific Maternal Antibodies
Schlereth B, Rose J, Buonocore L, ter Meulen V, Niewiesk S. Successful Vaccine-Induced Seroconversion by Single-Dose Immunization in the Presence of Measles Virus-Specific Maternal Antibodies. Journal Of Virology 2000, 74: 4652-4657. DOI: 10.1128/.74.10.4652-4657.2000.Peer-Reviewed Original Research
1999
Replication-Competent Rhabdoviruses with Human Immunodeficiency Virus Type 1 Coats and Green Fluorescent Protein: Entry by a pH-Independent Pathway
Boritz E, Gerlach J, Johnson J, Rose J. Replication-Competent Rhabdoviruses with Human Immunodeficiency Virus Type 1 Coats and Green Fluorescent Protein: Entry by a pH-Independent Pathway. Journal Of Virology 1999, 73: 6937-6945. PMID: 10400792, PMCID: PMC112779, DOI: 10.1128/jvi.73.8.6937-6945.1999.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCD4 AntigensCD4-Positive T-LymphocytesCell LineCricetinaeGreen Fluorescent ProteinsHeLa CellsHIV AntibodiesHIV Envelope Protein gp160HIV-1HumansHydrogen-Ion ConcentrationLigandsLuminescent ProteinsNeutralization TestsReceptors, CCR5Receptors, CXCR4Receptors, HIVRecombination, GeneticVesicular stomatitis Indiana virusVirus ReplicationConceptsVesicular stomatitis virusHuman immunodeficiency virus type 1 (HIV-1) envelope proteinSurrogate virusesRecombinant vesicular stomatitis virusPH-independent pathwayHIV bindingHIV vaccineHIV receptor CD4Coreceptor CXCR4HIV entryCoreceptor specificitySDF-1HIVReceptor CD4Single transmembrane glycoproteinAntibodiesVirusCD4Envelope proteinStomatitis virusCXCR4InfectionTransmembrane glycoproteinGreen fluorescent proteinAdditional recombinants
1985
Vaccinia Virus Recombinants: Expression of VSV Genes and Protective Immunization of Mice and Cattle
Mackett M, Yilma T, Rose J, Moss B. Vaccinia Virus Recombinants: Expression of VSV Genes and Protective Immunization of Mice and Cattle. Science 1985, 227: 433-435. PMID: 2981435, DOI: 10.1126/science.2981435.Peer-Reviewed Original ResearchConceptsVesicular stomatitis virusLive recombinant virusIntradermal vaccinationIntravenous challengeLethal encephalitisProtective immunizationVaccinia virus promoterDegree of protectionVaccinationContagious diseaseG proteinsStomatitis virusMiceMessenger RNAAntibodiesRecombinant virusesVirus promoterVirusVSV genesN proteinDNA copies