2016
Association of Drinking Problems and Duration of Alcohol Use to Inhibitory Control in Nondependent Young Adult Social Drinkers
Hu S, Zhang S, Chao HH, Krystal JH, Li CS. Association of Drinking Problems and Duration of Alcohol Use to Inhibitory Control in Nondependent Young Adult Social Drinkers. Alcohol Clinical And Experimental Research 2016, 40: 319-328. PMID: 26833431, PMCID: PMC4742397, DOI: 10.1111/acer.12964.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlcohol DrinkingAlcoholismBrainCase-Control StudiesFemaleFunctional NeuroimagingHumansInhibition, PsychologicalMagnetic Resonance ImagingMaleSelf-ControlConceptsAlcohol Use Disorders Identification TestYears of drinkingStop-signal reaction timeAlcohol useAge-related changesAlcohol misuseInhibitory controlAUDIT scoresDrinking problemsNondependent drinkersProlonged stop signal reaction timeChronic alcohol useAnterior cingulate cortexPresupplementary motor areaDisorders Identification TestRight inferior frontal gyrusResponse inhibitionSuperior temporal gyrusYoung adult social drinkersFunctional magnetic resonanceAdult social drinkersSignal reaction timeCerebral responsesInferior frontal gyrusHigher AUDIT
2014
Psychometrically Improved, Abbreviated Versions of Three Classic Measures of Impulsivity and Self-Control
Morean ME, DeMartini KS, Leeman RF, Pearlson GD, Anticevic A, Krishnan-Sarin S, Krystal JH, O’Malley S. Psychometrically Improved, Abbreviated Versions of Three Classic Measures of Impulsivity and Self-Control. Psychological Assessment 2014, 26: 1003-1020. PMID: 24885848, PMCID: PMC4152397, DOI: 10.1037/pas0000003.Peer-Reviewed Original ResearchConceptsBrief Self-Control ScaleSelf-reported impulsivityBIS/BASTest-criterion relationshipsFactor structureImpulsivity measuresMeasurement invarianceSelf-report impulsivity measuresBarratt Impulsiveness Scale-11Self-Control ScaleScalar measurement invarianceLatent factor structureGood scale propertiesComprehensive psychometric evaluationReplicable factor structureDrinking/smokingConfirmatory factor analysisAbbreviated versionAlternative factor structuresBehavioral inhibitionActivation ScalesSelf-ControlBIS-11Substance use researchSmoking outcomes
2012
Memantine, an NMDA receptor antagonist, differentially influences Go/No-Go performance and fMRI activity in individuals with and without a family history of alcoholism
Jamadar S, DeVito EE, Jiantonio RE, Meda SA, Stevens MC, Potenza MN, Krystal JH, Pearlson GD. Memantine, an NMDA receptor antagonist, differentially influences Go/No-Go performance and fMRI activity in individuals with and without a family history of alcoholism. Psychopharmacology 2012, 222: 129-140. PMID: 22311382, PMCID: PMC3674025, DOI: 10.1007/s00213-011-2628-2.Peer-Reviewed Original ResearchConceptsNMDA receptor antagonistFamily historyFHN subjectsReceptor antagonistFHP subjectsN-methyl-D-aspartate receptor functionReceptor functionIdentical-appearing placeboEffects of memantineFMRI activityNMDA receptor functionCorrect rejectsSingle doseMemantineGo/No-Go taskSeparate daysTemporal regionsCingulate activation
2005
Fore-period effect and stop-signal reaction time
Li CS, Krystal JH, Mathalon DH. Fore-period effect and stop-signal reaction time. Experimental Brain Research 2005, 167: 305-309. PMID: 16160823, DOI: 10.1007/s00221-005-0110-2.Peer-Reviewed Original ResearchMeSH KeywordsAttentionChoice BehaviorHumansInhibition, PsychologicalPsychomotor PerformanceReaction TimeSet, Psychology
1999
Comparison of four components of sensory gating in schizophrenia and normal subjects: a preliminary report
Boutros N, Belger A, Campbell D, D’Souza C, Krystal J. Comparison of four components of sensory gating in schizophrenia and normal subjects: a preliminary report. Psychiatry Research 1999, 88: 119-130. PMID: 10622348, DOI: 10.1016/s0165-1781(99)00074-8.Peer-Reviewed Original ResearchConceptsNormal control subjectsSchizophrenia patientsSensory gatingControl subjectsNormal subjectsSex-matched normal control subjectsPathophysiology of schizophreniaStimulus repetitionStable schizophrenia patientsSchizophrenia subjectsSimilar abnormalitiesPatientsPreliminary reportDysfunctionDegree of attenuationSchizophreniaLate phaseSubjectsDeviant stimuliStimulus changeIrrelevant stimuliPathophysiologyStimuliPotential paradigmAbnormalities