2012
Reward-Related Dorsal Striatal Activity Differences between Former and Current Cocaine Dependent Individuals during an Interactive Competitive Game
Hyatt CJ, Assaf M, Muska CE, Rosen RI, Thomas AD, Johnson MR, Hylton JL, Andrews MM, Reynolds BA, Krystal JH, Potenza MN, Pearlson GD. Reward-Related Dorsal Striatal Activity Differences between Former and Current Cocaine Dependent Individuals during an Interactive Competitive Game. PLOS ONE 2012, 7: e34917. PMID: 22606228, PMCID: PMC3351439, DOI: 10.1371/journal.pone.0034917.Peer-Reviewed Original ResearchImpaired Visual Cortical Plasticity in Schizophrenia
Çavuş I, Reinhart RM, Roach BJ, Gueorguieva R, Teyler TJ, Clapp WC, Ford JM, Krystal JH, Mathalon DH. Impaired Visual Cortical Plasticity in Schizophrenia. Biological Psychiatry 2012, 71: 512-520. PMID: 22364738, PMCID: PMC3292767, DOI: 10.1016/j.biopsych.2012.01.013.Peer-Reviewed Original ResearchConceptsHigh-frequency stimulationVisual cortical plasticityCortical plasticityVisual steady-state responseN-methyl-D-aspartate receptor functionHealthy control subjectsLong-term potentiation paradigmLong-term potentiationForm of neuroplasticityRepetitive visual stimulationSustained potentiationControl subjectsVEP assessmentSchizophrenia patientsStandard visual stimuliInfrequent target stimuliCore pathophysiologyReceptor functionPotentiationSchizophreniaVisual stimulationComponent scoresStimulationVisual stimuliBaseline
2002
Impact of intravenous nicotine on BOLD signal response to photic stimulation
Jacobsen LK, Gore JC, Skudlarski P, Lacadie CM, Jatlow P, Krystal JH. Impact of intravenous nicotine on BOLD signal response to photic stimulation. Magnetic Resonance Imaging 2002, 20: 141-145. PMID: 12034334, DOI: 10.1016/s0730-725x(02)00494-0.Peer-Reviewed Original ResearchMeSH KeywordsHumansInfusions, IntravenousMagnetic Resonance ImagingNicotinePhotic StimulationVisual CortexConceptsBOLD signal responseFunctional magnetic resonance imagingPhotic stimulationIntravenous infusionNeuronal activitySuccessive intravenous infusionsBlood oxygen level-dependent (BOLD) signalEffects of nicotineLevel-dependent signalMagnetic resonance imagingHealthy smokersVascular effectsTobacco smokingBrain effectsNicotine receptorsIntravenous nicotineEvidence of alterationsOccipital cortexVisual cortexResonance imagingNicotineBOLD signalStimulationInfusionCortex
1991
Visual stimulation increases technetium-99m-HMPAO distribution in human visual cortex.
Woods SW, Hegeman IM, Zubal IG, Krystal JH, Koster K, Smith EO, Heninger GR, Hoffer PB. Visual stimulation increases technetium-99m-HMPAO distribution in human visual cortex. Journal Of Nuclear Medicine 1991, 32: 210-5. PMID: 1992020.Peer-Reviewed Original ResearchConceptsRegional cerebral blood flowRelative rCBF increasesVisual cortex relativeHexamethylpropylene amine oximeCerebral blood flowMBq 99mTc-HMPAOSingle photon emissionHuman visual cortexRCBF increasesAmine oximePhysiologic changesCortex relativeHealthy subjectsBlood flowStriate cortexHMPAO distributionWhole brainVisual cortexPhotic stimulationSeparate daysAbility of changesVisual stimulationStimulation conditionsImages of distributionsSignificant increase