2001
Elevated motor threshold in drug-free, cocaine-dependent patients assessed with transcranial magnetic stimulation
Boutros N, Lisanby S, Tokuno H, Torello M, Campbell D, Berman R, Malison R, Krystal J, Kosten T. Elevated motor threshold in drug-free, cocaine-dependent patients assessed with transcranial magnetic stimulation. Biological Psychiatry 2001, 49: 369-373. PMID: 11239908, DOI: 10.1016/s0006-3223(00)00948-3.Peer-Reviewed Original ResearchConceptsTranscranial magnetic stimulationCortical excitabilityCocaine-dependent subjectsMotor thresholdControl subjectsMagnetic stimulationSingle-pulse transcranial magnetic stimulationExcitatory/inhibitory balancePulse transcranial magnetic stimulationChronic cocaine abuseMotor cortical regionsChronic cocaine abusersNormal control subjectsNumber of neurotransmittersAlters cortical excitabilityCocaine-dependent patientsCortical inhibitoryCerebral cortexInhibitory balanceAwake subjectsChronic cocaineCocaine intoxicationCocaine abusePsychiatric populationsCortical regions
1992
Startle gating deficits occur across prepulse intensities in schizophrenic patients
Grillon C, Ameli R, Charney D, Krystal J, Braff D. Startle gating deficits occur across prepulse intensities in schizophrenic patients. Biological Psychiatry 1992, 32: 939-943. PMID: 1467378, DOI: 10.1016/0006-3223(92)90183-z.Peer-Reviewed Original ResearchConceptsPrepulse inhibitionPrepulse stimulusSchizophrenic patientsStartle reflexControl groupStartle gating deficitsCentral inhibitory mechanismsDeficient prepulse inhibitionGating deficitsStartling stimulusNormal controlsPatientsReflexPrepulse intensityInhibitory mechanismFurther studiesStimuliInhibitionGroup