2022
Meeting a threat of the Anthropocene: Taste avoidance of metal ions by Drosophila
Xiao S, Baik LS, Shang X, Carlson JR. Meeting a threat of the Anthropocene: Taste avoidance of metal ions by Drosophila. Proceedings Of The National Academy Of Sciences Of The United States Of America 2022, 119: e2204238119. PMID: 35700364, PMCID: PMC9231609, DOI: 10.1073/pnas.2204238119.Peer-Reviewed Original ResearchConceptsGenerations of exposureDipteran speciesAnthropogenic stressorsGR familyEnvironmental changesToxic chemical compoundsBitter-sensing neuronsTaste organsTaste receptorsAvoidance of feedingSugar-sensing neuronsElevated concentrationsZinc ionsDrosophilaChemical compoundsInsectsHuman activitiesBehavioral responsesReceptorsOrganismsFliesSpeciesNeuronsRapid rateDifferent subsetsIr56b is an atypical ionotropic receptor that underlies appetitive salt response in Drosophila
Dweck HKM, Talross GJS, Luo Y, Ebrahim SAM, Carlson JR. Ir56b is an atypical ionotropic receptor that underlies appetitive salt response in Drosophila. Current Biology 2022, 32: 1776-1787.e4. PMID: 35294865, PMCID: PMC9050924, DOI: 10.1016/j.cub.2022.02.063.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsDrosophilaDrosophila melanogasterDrosophila ProteinsSodium ChlorideTasteTaste PerceptionConceptsSalt tasteBitter-sensing neuronsStop codonLoss of functionNumber of speciesIonotropic receptorsIonotropic receptor familyN-terminal regionReceptor familyNeuronsDrosophila speciesPremature stop codonTaste modalitiesAncient functionGR familySalt responseSense codonsMolecular basisAtypical memberSalt detectionModalitiesCodonSensory modalitiesDrosophilaBehavioral responses
2019
Molecular Logic and Evolution of Bitter Taste in Drosophila
Dweck HKM, Carlson JR. Molecular Logic and Evolution of Bitter Taste in Drosophila. Current Biology 2019, 30: 17-30.e3. PMID: 31839451, PMCID: PMC6946858, DOI: 10.1016/j.cub.2019.11.005.Peer-Reviewed Original Research
2017
A receptor and neuron that activate a circuit limiting sucrose consumption
Joseph RM, Sun JS, Tam E, Carlson JR. A receptor and neuron that activate a circuit limiting sucrose consumption. ELife 2017, 6: e24992. PMID: 28332980, PMCID: PMC5388533, DOI: 10.7554/elife.24992.Peer-Reviewed Original Research
2016
Bitter taste receptors confer diverse functions to neurons
Delventhal R, Carlson JR. Bitter taste receptors confer diverse functions to neurons. ELife 2016, 5: e11181. PMID: 26880560, PMCID: PMC4764594, DOI: 10.7554/elife.11181.Peer-Reviewed Original Research