2008
A New Drosophila POU Gene, pdm3, Acts in Odor Receptor Expression and Axon Targeting of Olfactory Neurons
Tichy AL, Ray A, Carlson JR. A New Drosophila POU Gene, pdm3, Acts in Odor Receptor Expression and Axon Targeting of Olfactory Neurons. Journal Of Neuroscience 2008, 28: 7121-7129. PMID: 18614681, PMCID: PMC2572001, DOI: 10.1523/jneurosci.2063-08.2008.Peer-Reviewed Original ResearchConceptsPOU genesOlfactory receptor neuronsAxon targetingReceptor gene choiceClasses of ORNsReceptor expressionGenetic interactionsGene choiceGene codesORN classesPdm3Genetic analysisMutational analysisOdor responsesMolecular mechanismsGenesOlfactory neuronsReceptor neuronsIndividual receptorsDifferential activationOlfactory systemProper transmissionExpressionFunctional organizationTargeting
1999
The Odor Specificities of a Subset of Olfactory Receptor Neurons Are Governed by Acj6, a POU-Domain Transcription Factor
Clyne P, Certel S, de Bruyne M, Zaslavsky L, Johnson W, Carlson J. The Odor Specificities of a Subset of Olfactory Receptor Neurons Are Governed by Acj6, a POU-Domain Transcription Factor. Neuron 1999, 22: 339-347. PMID: 10069339, DOI: 10.1016/s0896-6273(00)81094-6.Peer-Reviewed Original ResearchConceptsPOU domain transcription factorOlfactory neuronsTranscription factorsIndividual olfactory neuronsOdorant response profilesSubset of neuronsOlfactory receptor neuronsOdor specificityPhysiological analysisAcj6Neuronal identityOlfactory behaviorMolecular analysisReceptor neuronsNeuronsReceptor geneOlfactory codingGenesResponse profilesMutantsSpecificitySubsetA Novel Family of Divergent Seven-Transmembrane Proteins Candidate Odorant Receptors in Drosophila
Clyne P, Warr C, Freeman M, Lessing D, Kim J, Carlson J. A Novel Family of Divergent Seven-Transmembrane Proteins Candidate Odorant Receptors in Drosophila. Neuron 1999, 22: 327-338. PMID: 10069338, DOI: 10.1016/s0896-6273(00)81093-4.Peer-Reviewed Original ResearchConceptsOlfactory receptor neuronsPOU domain transcription factorLarge multigene familyCandidate odorant receptorsTransmembrane domain proteinGenomic sequence databasesSubset of ORNsDomain proteinsMultigene familyAntennal developmentOdorant receptorsTranscription factorsSequence databasesInitiate expressionOlfactory organOdorant specificityNovel familyDifferent membersReceptor neuronsReceptor moleculesInsectsMutantsValuable modelGenesOlfactory system