2018
Verticalization of bacterial biofilms
Beroz F, Yan J, Meir Y, Sabass B, Stone H, Bassler B, Wingreen N. Verticalization of bacterial biofilms. Nature Physics 2018, 14: 954-960. PMID: 30906420, PMCID: PMC6426328, DOI: 10.1038/s41567-018-0170-4.Peer-Reviewed Original ResearchSingle-cell resolutionCommunities of bacteriaRod-shaped bacteriaFounder cellsThree-dimensional structureCell divisionBiofilm developmentFlat biofilmsCell growthShort cellsCell lengthLong cellsCellular scaleBacterial biofilmsBiofilm clustersBiofilmsCellsBacteriaEffective surface pressureSuch changesDivisionGrowth
2017
Extracellular-matrix-mediated osmotic pressure drives Vibrio cholerae biofilm expansion and cheater exclusion
Yan J, Nadell CD, Stone HA, Wingreen NS, Bassler BL. Extracellular-matrix-mediated osmotic pressure drives Vibrio cholerae biofilm expansion and cheater exclusion. Nature Communications 2017, 8: 327. PMID: 28835649, PMCID: PMC5569112, DOI: 10.1038/s41467-017-00401-1.Peer-Reviewed Original ResearchConceptsBiofilm-forming bacterial speciesSurface-attached communitiesVibrio choleraeActive cell growthModel organismsMatrix-producing cellsBacterial lifeNutrient uptakeEnvironmental perturbationsBacterial speciesBacterial cellsPlanktonic cellsSubmerged biofilmsExtracellular matrixCell growthMatrix productionOsmotic pressureBiofilm growthBiofilmsCholeraeCellsPhysical exclusionMatrix crosslinkingOsmotic swellingGrowth