2021
RNA stabilization by a poly(A) tail 3′-end binding pocket and other modes of poly(A)-RNA interaction
Torabi SF, Vaidya AT, Tycowski KT, DeGregorio SJ, Wang J, Shu MD, Steitz TA, Steitz JA. RNA stabilization by a poly(A) tail 3′-end binding pocket and other modes of poly(A)-RNA interaction. Science 2021, 371 PMID: 33414189, PMCID: PMC9491362, DOI: 10.1126/science.abe6523.Peer-Reviewed Original ResearchMeSH KeywordsCrystallizationNucleic Acid ConformationOryzaPoly APolyadenylationRNA StabilityRNA, Messenger
2017
Crystal structure of Pistol, a class of self-cleaving ribozyme
Nguyen LA, Wang J, Steitz TA. Crystal structure of Pistol, a class of self-cleaving ribozyme. Proceedings Of The National Academy Of Sciences Of The United States Of America 2017, 114: 1021-1026. PMID: 28096403, PMCID: PMC5293083, DOI: 10.1073/pnas.1611191114.Peer-Reviewed Original Research
2015
Crystallographic study of a MATE transporter presents a difficult case in structure determination with low‐resolution, anisotropic data and crystal twinning
Symersky J, Guo Y, Wang J, Lu M. Crystallographic study of a MATE transporter presents a difficult case in structure determination with low‐resolution, anisotropic data and crystal twinning. Acta Crystallographica Section D, Structural Biology 2015, 71: 2287-2296. PMID: 26527145, PMCID: PMC4631480, DOI: 10.1107/s1399004715016995.Peer-Reviewed Original Research
2012
Structural Basis for Differential Insertion Kinetics of dNMPs Opposite a Difluorotoluene Nucleotide Residue
Xia S, Eom SH, Konigsberg WH, Wang J. Structural Basis for Differential Insertion Kinetics of dNMPs Opposite a Difluorotoluene Nucleotide Residue. Biochemistry 2012, 51: 1476-1485. PMID: 22304682, PMCID: PMC3292180, DOI: 10.1021/bi2016487.Peer-Reviewed Original Research
2009
Application of general formulas for the correction of a lattice‐translocation defect in crystals of a lentiviral integrase in complex with LEDGF
Hare S, Cherepanov P, Wang J. Application of general formulas for the correction of a lattice‐translocation defect in crystals of a lentiviral integrase in complex with LEDGF. Acta Crystallographica Section D, Structural Biology 2009, 65: 966-973. PMID: 19690374, DOI: 10.1107/s0907444909023695.Peer-Reviewed Original Research
2008
Mechanism of Inhibition of Human Immunodeficiency Virus Type 1 Reverse Transcriptase by a Stavudine Analogue, 4′-Ethynyl Stavudine Triphosphate
Yang G, Wang J, Cheng Y, Dutschman GE, Tanaka H, Baba M, Cheng YC. Mechanism of Inhibition of Human Immunodeficiency Virus Type 1 Reverse Transcriptase by a Stavudine Analogue, 4′-Ethynyl Stavudine Triphosphate. Antimicrobial Agents And Chemotherapy 2008, 52: 2035-2042. PMID: 18391035, PMCID: PMC2415781, DOI: 10.1128/aac.00083-08.Peer-Reviewed Original ResearchConceptsM184V mutantNucleoside reverse transcriptase inhibitorHuman immunodeficiency virus type 1Immunodeficiency virus type 1Human immunodeficiency virus type 1 reverse transcriptaseReverse transcriptase inhibitorType 1 reverse transcriptaseVirus type 1Mechanism of inhibitionHIV-1 RTWild-type RTStavudine triphosphateTranscriptase inhibitorD4TD4TTPType 1WT RTMutant RTsReverse transcriptase
2007
Crystal structure of Bacillus subtilis CodW, a noncanonical HslV‐like peptidase with an impaired catalytic apparatus
Rho S, Park HH, Kang GB, Im YJ, Kang MS, Lim BK, Seong IS, Seol J, Chung CH, Wang J, Eom SH. Crystal structure of Bacillus subtilis CodW, a noncanonical HslV‐like peptidase with an impaired catalytic apparatus. Proteins Structure Function And Bioinformatics 2007, 71: 1020-1026. PMID: 17979190, DOI: 10.1002/prot.21758.Peer-Reviewed Original Research
2005
Correction of X‐ray intensities from an HslV–HslU co‐crystal containing lattice‐translocation defects
Wang J, Rho SH, Park HH, Eom SH. Correction of X‐ray intensities from an HslV–HslU co‐crystal containing lattice‐translocation defects. Acta Crystallographica Section D, Structural Biology 2005, 61: 932-941. PMID: 15983416, DOI: 10.1107/s0907444905009546.Peer-Reviewed Original Research
2004
Correction of X‐ray intensities from single crystals containing lattice‐translocation defects
Wang J, Kamtekar S, Berman AJ, Steitz TA. Correction of X‐ray intensities from single crystals containing lattice‐translocation defects. Acta Crystallographica Section D, Structural Biology 2004, 61: 67-74. PMID: 15608377, DOI: 10.1107/s0907444904026721.Peer-Reviewed Original ResearchCrystal structure of a self-splicing group I intron with both exons
Adams PL, Stahley MR, Kosek AB, Wang J, Strobel SA. Crystal structure of a self-splicing group I intron with both exons. Nature 2004, 430: 45-50. PMID: 15175762, DOI: 10.1038/nature02642.Peer-Reviewed Original Research
2003
A second response in correcting the HslV–HslU quaternary structure
Wang J. A second response in correcting the HslV–HslU quaternary structure. Journal Of Structural Biology 2003, 141: 7-8. PMID: 12576015, DOI: 10.1016/s1047-8477(02)00629-9.Peer-Reviewed Original Research
2001
A Corrected Quaternary Arrangement of the Peptidase HslV and ATPase HslU in a Cocrystal Structure
Wang J. A Corrected Quaternary Arrangement of the Peptidase HslV and ATPase HslU in a Cocrystal Structure. Journal Of Structural Biology 2001, 134: 15-24. PMID: 11469873, DOI: 10.1006/jsbi.2001.4347.Peer-Reviewed Original ResearchConceptsQuaternary arrangementATP-dependent HslVU proteaseHslV peptidaseTranslocation poreHslU ATPaseHslVU proteaseHexameric ringHslVCocrystal structureHslUSmall-angle X-ray scattering (SAXS) studiesCrystal structurePeptidaseATPaseCrystallographic analysisElectron microscopic studySpace group assignmentX-ray scattering studyBindsHexamerProtease