2009
Combining electron crystallography and X-ray crystallography to study the MlotiK1 cyclic nucleotide-regulated potassium channel
Clayton GM, Aller SG, Wang J, Unger V, Morais-Cabral JH. Combining electron crystallography and X-ray crystallography to study the MlotiK1 cyclic nucleotide-regulated potassium channel. Journal Of Structural Biology 2009, 167: 220-226. PMID: 19545635, PMCID: PMC2922748, DOI: 10.1016/j.jsb.2009.06.012.Peer-Reviewed Original ResearchConceptsS1-S4 domainMembrane protein structure determinationTetrameric cation channelsX-ray crystallographyProtein structure determinationPotassium channelsElectron crystallographyMlotiK1Cation channelsX-ray structureNew insightsProjection mapStructure determinationCrystallographyCombined applicationDomainUseful strategyQuality crystals
1999
New insights into the ATP‐dependent Clp protease: Escherichia coli and beyond
Porankiewicz J, Wang J, Clarke A. New insights into the ATP‐dependent Clp protease: Escherichia coli and beyond. Molecular Microbiology 1999, 32: 449-458. PMID: 10320569, DOI: 10.1046/j.1365-2958.1999.01357.x.Peer-Reviewed Original ResearchConceptsClp proteaseClpP proteinATP-dependent Clp proteaseClp/Hsp100Escherichia coliKey metabolic enzymesPrecise regulatory mechanismsChaperone subunitsPhotosynthetic organismsHigher plantsRegulatory subunitCellular processesHeptameric ringsHexameric ringThree-dimensional structureProteolytic subunitNew insightsRegulatory mechanismsProtein turnoverMetabolic enzymesFunctional importanceSubunitsProteaseRecent findingsProtein