2020
Fewer gastrointestinal bleeds with ticagrelor and prasugrel compared with clopidogrel in patients with acute coronary syndrome following percutaneous coronary intervention
Abraham NS, Yang EH, Noseworthy PA, Inselman J, Yao X, Herrin J, Sangaralingham LR, Ngufor C, Shah ND. Fewer gastrointestinal bleeds with ticagrelor and prasugrel compared with clopidogrel in patients with acute coronary syndrome following percutaneous coronary intervention. Alimentary Pharmacology & Therapeutics 2020, 52: 646-654. PMID: 32657466, PMCID: PMC8183594, DOI: 10.1111/apt.15790.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAgedClopidogrelCohort StudiesFemaleGastrointestinal HemorrhageHumansMaleMiddle AgedPercutaneous Coronary InterventionPlatelet Aggregation InhibitorsPostoperative ComplicationsPrasugrel HydrochlorideRetrospective StudiesThromboembolismTicagrelorTreatment OutcomeUnited StatesConceptsPercutaneous coronary interventionAcute coronary syndromeGIB ratesGIB riskCoronary syndromeGastrointestinal bleedingSTEMI patientsCoronary interventionHazard ratioMajor adverse cardiac eventsRisk reductionCox proportional hazards modelNSTE-ACS patientsAdverse cardiac eventsMajor bleeding eventsConfidence intervalsInverse probability treatmentProportional hazards modelMedicare Advantage enrolleesBleeding eventsClopidogrel prescriptionGIB eventsNSTE-ACSGastrointestinal bleedBaseline characteristics
2016
Development and validation of a simple risk score to predict 30‐day readmission after percutaneous coronary intervention in a cohort of medicare patients
Minges KE, Herrin J, Fiorilli PN, Curtis JP. Development and validation of a simple risk score to predict 30‐day readmission after percutaneous coronary intervention in a cohort of medicare patients. Catheterization And Cardiovascular Interventions 2016, 89: 955-963. PMID: 27515069, PMCID: PMC5397364, DOI: 10.1002/ccd.26701.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAlgorithmsDecision Support TechniquesFemaleHumansLogistic ModelsMaleMedicareMultivariate AnalysisOdds RatioPatient ReadmissionPercutaneous Coronary InterventionPredictive Value of TestsRegistriesReproducibility of ResultsRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeUnited StatesConceptsRisk of readmissionPCI patientsRisk scoreMultivariable logistic regression modelRisk score developmentDays of dischargeSimple risk scoreTime of dischargeModel c-statisticLogistic regression modelsStepwise selection modelCathPCI RegistryHospital dischargeReadmission ratesClinical factorsRevascularization proceduresValidation cohortC-statisticReadmissionHigh riskMedicare feeLower riskService claimsPatientsCohort
2015
Association of Physician Certification in Interventional Cardiology With In-Hospital Outcomes of Percutaneous Coronary Intervention
Fiorilli PN, Minges KE, Herrin J, Messenger JC, Ting HH, Nallamothu BK, Lipner RS, Hess BJ, Holmboe ES, Brennan JJ, Curtis JP. Association of Physician Certification in Interventional Cardiology With In-Hospital Outcomes of Percutaneous Coronary Intervention. Circulation 2015, 132: 1816-1824. PMID: 26384518, PMCID: PMC4641797, DOI: 10.1161/circulationaha.115.017523.Peer-Reviewed Original ResearchMeSH KeywordsAgedCardiology Service, HospitalCertificationFemaleHospital MortalityHumansMaleMiddle AgedPercutaneous Coronary InterventionPhysiciansRisk FactorsTreatment OutcomeConceptsEmergency coronary artery bypassPercutaneous coronary interventionCoronary artery bypassArtery bypassVascular complicationsHospital mortalityEnd pointHospital outcomesCoronary interventionPCI proceduresIn-Hospital OutcomesPrimary end pointSecondary end pointsComposite end pointRisk of bleedingHierarchical multivariable modelInternal Medicine certificationAmerican BoardCathPCI RegistryPatient characteristicsPCI volumeUnadjusted outcomesAdverse outcomesPatient outcomesMultivariable model