2013
Imaging-genetics in dyslexia: Connecting risk genetic variants to brain neuroimaging and ultimately to reading impairments
Eicher JD, Gruen JR. Imaging-genetics in dyslexia: Connecting risk genetic variants to brain neuroimaging and ultimately to reading impairments. Molecular Genetics And Metabolism 2013, 110: 201-212. PMID: 23916419, PMCID: PMC3800223, DOI: 10.1016/j.ymgme.2013.07.001.Peer-Reviewed Original Research
2012
Variants in the DYX2 locus are associated with altered brain activation in reading-related brain regions in subjects with reading disability
Cope N, Eicher JD, Meng H, Gibson CJ, Hager K, Lacadie C, Fulbright RK, Constable RT, Page GP, Gruen JR. Variants in the DYX2 locus are associated with altered brain activation in reading-related brain regions in subjects with reading disability. NeuroImage 2012, 63: 148-156. PMID: 22750057, PMCID: PMC3518451, DOI: 10.1016/j.neuroimage.2012.06.037.Peer-Reviewed Original Research
2010
A Dyslexia-Associated Variant in DCDC2 Changes Gene Expression
Meng H, Powers NR, Tang L, Cope NA, Zhang PX, Fuleihan R, Gibson C, Page GP, Gruen JR. A Dyslexia-Associated Variant in DCDC2 Changes Gene Expression. Behavior Genetics 2010, 41: 58-66. PMID: 21042874, PMCID: PMC3053575, DOI: 10.1007/s10519-010-9408-3.Peer-Reviewed Original Research
2005
DCDC2 is associated with reading disability and modulates neuronal development in the brain
Meng H, Smith SD, Hager K, Held M, Liu J, Olson RK, Pennington BF, DeFries JC, Gelernter J, O'Reilly-Pol T, Somlo S, Skudlarski P, Shaywitz SE, Shaywitz BA, Marchione K, Wang Y, Paramasivam M, LoTurco JJ, Page GP, Gruen JR. DCDC2 is associated with reading disability and modulates neuronal development in the brain. Proceedings Of The National Academy Of Sciences Of The United States Of America 2005, 102: 17053-17058. PMID: 16278297, PMCID: PMC1278934, DOI: 10.1073/pnas.0508591102.Peer-Reviewed Original Research
1991
Differential expression of novel Gsα signal transduction protein cDNA species
Swaroop A, Agarwal N, Gruen J, Bick D, Weissman S. Differential expression of novel Gsα signal transduction protein cDNA species. Nucleic Acids Research 1991, 19: 4725-4729. PMID: 1716359, PMCID: PMC328715, DOI: 10.1093/nar/19.17.4725.Peer-Reviewed Original ResearchConceptsCDNA speciesAlpha speciesDifferential expressionSignal transduction proteinsAlpha cDNA cloneTransduction proteinsHeterotrimeric complexCDNA clonesAlternative promotersNovel exonsAlternate splicingAUG codonHuman adult retinaMembrane receptorsGs alphaNovel signalSpeciesSpecific oligonucleotide probesOligonucleotide probesSitu hybridizationExon 2Total RNASpecific primersMolecular heterogeneityAdult retina