2002
Consequences and Determinants of Adherence to Antiretroviral Medication: Results from Adult Aids Clinical Trials Group Protocol 370
Ickovics J, Cameron A, Zackin R, Bassett R, Chesney M, Johnson VA, Kuritzkes DR, Acosta E, Barnett R, Bell D, Cannmann S, Eron J, Fischl M, Marschner I, Martinez A, Morse G, Pettinelli C, Sommadossi J, Wood K, Murphy R, Priller N, Sha B, French N, van der Horst C, Marcus C, Lane T, Horton J, Schooley R, Putnam B, Shugarts D, Johnson S, Fife K, Black J, Heise D, Todd K, Bagur J, Vazquez G, Lopez I, Ramirez V, Hill R, Wright S, McCulloch B, Saag M, Slamowitz D, Cain P, Merigan T, Tallman V, Greisberger C, Shoemaker M, Lewis M, Hewitt R, Havlir D, Nuffer K, Wininger D, Watson S, Clark J, Jackson C, Rodriguez A, Scerpella E, Tebas P, Stiffler T, Royal M, Powderly W, Collier A, Storey S, Houseworth L, Conley N, Lederman M, Kalayjian B, Ingersol K, McVey R, Gluckman S, Helker C, Kappes R, Kim D, Albrecht M, Koziol C, Govan; T, Miles S, Chafey S, Mitsuyasu R, Sacks H, Mildvan D, Shikuma C, Millard M, Souza S. Consequences and Determinants of Adherence to Antiretroviral Medication: Results from Adult Aids Clinical Trials Group Protocol 370. Antiviral Therapy 2002, 7: 185-193. PMID: 12487386, DOI: 10.1177/135965350200700308.Peer-Reviewed Original ResearchConceptsPlasma HIV-1 RNA levelsHIV-1 RNA levelsCD4 cell countWeek 24Adherence ratesClinical trialsBaseline plasma HIV-1 RNA levelsAdult AIDS Clinical Trials GroupCell countAIDS Clinical Trials GroupRNA levelsAIDS clinical trialsAdverse clinical eventsAssociation of adherenceOverall adherence rateDeterminants of adherenceClinical Trials GroupSelf-reported adherencePredictors of adherencePatterns of adherenceNon-nucleoside reversePotential confounding variablesVirological outcomesAntiretroviral therapyAdverse events
2001
Self-reported zidovudine adherence among pregnant women with human immunodeficiency virus infection in four US states
Wilson T, Ickovics J, Fernandez M, Koenig L, Walter E, Project F. Self-reported zidovudine adherence among pregnant women with human immunodeficiency virus infection in four US states. American Journal Of Obstetrics And Gynecology 2001, 184: 1235-1240. PMID: 11349194, DOI: 10.1067/mob.2001.114032.Peer-Reviewed Original ResearchConceptsPregnant womenHuman immunodeficiency virus-infected pregnant womenHuman immunodeficiency virus (HIV) infectionPrenatal illicit drug useImmunodeficiency virus infectionPrenatal care settingsIllicit drug useIllicit drug usersPrenatal zidovudineZidovudine dosesZidovudine useZidovudine therapyWeeks' gestationPrenatal vitaminsIncomplete adherencePrenatal clinicsRegimen adherenceVirus infectionCare settingsPsychosocial factorsDrug usersDrug useMultivariate analysisWomenAdherence
2000
Self-reported adherence to antiretroviral medications among participants in HIV clinical trials: The AACTG Adherence Instruments
Chesney M, Ickovics J, Chambers D, Gifford A, Neidig J, Zwickl B, Wu A, GROUP P. Self-reported adherence to antiretroviral medications among participants in HIV clinical trials: The AACTG Adherence Instruments. AIDS Care 2000, 12: 255-266. PMID: 10928201, DOI: 10.1080/09540120050042891.Peer-Reviewed Original ResearchConceptsAdult AIDS Clinical Trials GroupCent of patientsClinical trialsAntiretroviral therapyAdherence instrumentAIDS Clinical Trials GroupCombination antiretroviral therapyClinical Trials GroupSelf-reported adherenceHIV clinical trialsAdherent patientsAntiretroviral medicationsTrial groupLow adherenceSelf-report questionnairesCommon reasonPatientsDrug resistanceTrialsImproved healthMedicationsProtease inhibitorsQuestionnaireDoseAdherence
1999
Adherence: a necessity for successful HIV combination therapy.
Chesney M, Ickovics J, Hecht F, Sikipa G, Rabkin J. Adherence: a necessity for successful HIV combination therapy. AIDS 1999, 13 Suppl A: s271-8. PMID: 10885784.Peer-Reviewed Original ResearchConceptsCombination therapyHIV/AIDSHIV combination therapySuccessful treatment outcomeEmergence of resistancePatient adherenceClinical trialsDisease progressionLong-term benefitsRisk factorsHIV therapyTreatment outcomesTherapyAdherence researchResistant strainsHealth benefitsAdherenceIntervention programsVirus breakthroughAIDSIntervention effortsDifferent populationsValid methodFocused effortsHIV
1997
Issues Regarding Antiretroviral Treatment for Patients With HIV-1 Infection
Ickovics J, Chesney M. Issues Regarding Antiretroviral Treatment for Patients With HIV-1 Infection. JAMA 1997, 278: 1233-1234. PMID: 9333258, DOI: 10.1001/jama.1997.03550150037025.Peer-Reviewed Original ResearchMeSH KeywordsAnti-HIV AgentsClinical Trials as TopicDrug Therapy, CombinationHIV InfectionsHumansPractice Guidelines as TopicViral LoadConceptsAdherence behaviorPlasma human immunodeficiency virus (HIV) RNA levelsHuman immunodeficiency virus (HIV) RNA levelsDrug resistanceVirus RNA levelsHIV-1 infectionDrug regimenHIV diseaseAntiretroviral treatmentViral loadTreatment regimensCombination therapyPatients' willingnessDisease progressionCostly regimensConsensus statementMore pillsPatient healthRegimensRNA levelsAdherenceDearth of informationTherapyBrief periodNonadherence