2012
Age Effects on Serotonin Receptor 1B as Assessed by PET
Matuskey D, Pittman B, Planeta-Wilson B, Walderhaug E, Henry S, Gallezot JD, Nabulsi N, Ding YS, Bhagwagar Z, Malison R, Carson RE, Neumeister A. Age Effects on Serotonin Receptor 1B as Assessed by PET. Journal Of Nuclear Medicine 2012, 53: 1411-1414. PMID: 22851636, PMCID: PMC3690814, DOI: 10.2967/jnumed.112.103598.Peer-Reviewed Original ResearchConceptsMultilinear reference tissue modelGray matter atrophyReceptor 1BAge-related gray matter atrophyIndividual cortical regionsSerotonin receptor 1BPrevious imaging studiesSerotonin measuresReference tissue modelAge-related declineMatter atrophyHealthy subjectsHealthy adultsGray matterImaging studiesCortical regionsPET imagingSubject underwentMultiple comparisonsCortexNegative associationAge effectsAgeAtrophyPutamen
2011
Serotonin 1B receptor imaging in pathological gambling
Potenza MN, Walderhaug E, Henry S, Gallezot JD, Planeta-Wilson B, Ropchan J, Neumeister A. Serotonin 1B receptor imaging in pathological gambling. The World Journal Of Biological Psychiatry 2011, 14: 139-145. PMID: 21936763, PMCID: PMC3595502, DOI: 10.3109/15622975.2011.598559.Peer-Reviewed Original ResearchConceptsSerotonin 1B receptorAnterior cingulate cortexPathological gamblingCingulate cortexVentral striatumBPND valuesMedication-free subjectsSouth Oaks Gambling ScreenPositron emission scanningFunctional neuroimaging studiesSerotonergic mechanismsSerotonergic functionSerotonin receptorsCC subjectsComparison subjectsBrain regionsImaging studiesPG subjectsNeuroimaging studiesPotential roleReceptorsFurther studiesStriatumSubstance addictionCortex