2023
Pregnant Patients with a Documented History of Penicillin Allergy and Associated Maternal and Neonatal Outcomes at a Tertiary Care Center
Azmy V, Lundsberg L, Culhane J, Kwah J, Partridge C, Son M. Pregnant Patients with a Documented History of Penicillin Allergy and Associated Maternal and Neonatal Outcomes at a Tertiary Care Center. American Journal Of Perinatology 2023, 41: e2051-e2057. PMID: 37211008, DOI: 10.1055/a-2096-5002.Peer-Reviewed Original ResearchPenicillin allergy historyNon-β-lactam antibioticsPenicillin allergyNeonatal outcomesPregnant patientsAllergy historyPregnant individualsElectronic medical recordsMedical recordsMultivariable analysisPostpartum endometritisHigh riskLactam antibioticsSignificant differencesBad obstetric outcomeRetrospective cohort studyTertiary care centerPostnatal hospital stayWeeks of gestationLarge academic hospitalAssociated maternalEligible deliveriesHospital stayMaternal outcomesObstetric outcomesAntibiotic choice for Group B Streptococcus prophylaxis in mothers with reported penicillin allergy and associated newborn outcomes
Snider J, Mithal L, Kwah J, Rhodes N, Son M. Antibiotic choice for Group B Streptococcus prophylaxis in mothers with reported penicillin allergy and associated newborn outcomes. BMC Pregnancy And Childbirth 2023, 23: 400. PMID: 37254067, PMCID: PMC10228028, DOI: 10.1186/s12884-023-05697-0.Peer-Reviewed Original ResearchConceptsGroup B streptococcus prophylaxisReported penicillin allergyPenicillin allergyGBS prophylaxisLab drawsNeonatal outcomesNewborn outcomesAntibiotic administrationMedical recordsPregnant individualsIntrapartum group B streptococcus prophylaxisNeonatal intensive care unit admissionDesignThis retrospective cohort studyIntensive care unit admissionSelf-reported penicillin allergyNeonates of mothersCare unit admissionIntrapartum antibiotic prophylaxisRetrospective cohort studyWeeks of gestationMother-infant pairsMother-infant dyadsBeta-lactam antibioticsAntibiotic prophylaxisUnit admission
2022
Outpatient penicillin allergy evaluation during pregnancy and associated clinical outcomes
Kwah JH, Burn MS, Liao J, Cate J, Son M. Outpatient penicillin allergy evaluation during pregnancy and associated clinical outcomes. American Journal Of Obstetrics & Gynecology MFM 2022, 4: 100674. PMID: 35691578, DOI: 10.1016/j.ajogmf.2022.100674.Peer-Reviewed Original ResearchConceptsPenicillin allergy evaluationPenicillin allergyPregnant womenAllergy evaluationHospital stayNeonatal outcomesClinical benefitIntensive care unit admissionBirth hospitalization lengthUnverified penicillin allergyCare unit admissionNeonatal adverse outcomesRetrospective cohort studyMedical record reviewPostpartum hospital stayAdditional clinical benefitLarge academic hospitalElectronic medical recordsBeta-lactam antibioticsPostpartum infectionReferred womenUnit admissionMaternal outcomesCohort studyTrue allergy
2020
Clinical factors associated with acute exacerbations of chronic rhinosinusitis
Kwah JH, Somani SN, Stevens WW, Kern RC, Smith SS, Welch KC, Conley DB, Tan BK, Grammer LC, Yang A, Schleimer RP, Peters AT. Clinical factors associated with acute exacerbations of chronic rhinosinusitis. Journal Of Allergy And Clinical Immunology 2020, 145: 1598-1605. PMID: 32004523, PMCID: PMC8177481, DOI: 10.1016/j.jaci.2020.01.023.Peer-Reviewed Original ResearchConceptsFrequent acute exacerbationsChronic rhinosinusitisAcute exacerbationAllergic rhinitisClinical factorsEosinophil countAutoimmune diseasesSignificant health care burdenSinus disease severityRetrospective cohort studySystemic corticosteroid useHealth care burdenHigh-risk phenotypeAntibiotic allergyExacerbation frequencyFrequent exacerbationsSinus symptomsCorticosteroid useCohort studyLower FEVNasal polyposisAntibody deficiencyImpaired qualityImmunologic diseasesOdds ratio
2019
Prevalence and characterization of chronic rhinosinusitis in patients with non‒cystic fibrosis bronchiectasis at a tertiary care center in the United States
Somani SN, Kwah JH, Yeh C, Conley DB, Grammer LC, Kern RC, Prickett M, Schleimer RP, Smith SS, Stevens WW, Tan BK, Welch KC, Peters AT. Prevalence and characterization of chronic rhinosinusitis in patients with non‒cystic fibrosis bronchiectasis at a tertiary care center in the United States. International Forum Of Allergy & Rhinology 2019, 9: 1424-1429. PMID: 31589811, PMCID: PMC6913921, DOI: 10.1002/alr.22436.Peer-Reviewed Original ResearchConceptsPresence of CRSTertiary care centerChronic rhinosinusitisCare centerNon-cystic fibrosis bronchiectasisPrevalence of CRSConcomitant chronic rhinosinusitisRetrospective cohort studyGastroesophageal reflux diseasePeripheral eosinophil countPulmonary function testingTertiary medical centerNumerous comorbid conditionsTreatment of patientsUnited States populationBronchiectasis patientsFibrosis bronchiectasisReflux diseaseAllergic rhinitisCohort studyRadiographic evidenceAntibody deficiencyComorbid conditionsEosinophil countFunction testing