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INFORMATION FOR

    Janna D Helfrich, MD

    she/her/hers
    Assistant Professor
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    Contact Info

    Yale School of Medicine

    333 Cedar St, Dept of Anesthesiology

    New Haven, CT 06510

    United States

    About

    Titles

    Assistant Professor

    Appointments

    Other Departments & Organizations

    Education & Training

    Resident
    University Medical Center Tuebingen (2022)
    Postdoctoral Fellow
    University of California at Berkeley (2019)
    Resident
    University Medical Center Hamburg-Eppendorf (2016)
    Fellow, Intensive Care Medicine
    University Medical Center Hamburg Eppendorf (2016)
    Fellow, Prehospital Emergency Care
    University Medical Center Hamburg-Eppendorf (2015)
    PhD
    Charite University Medical Center, Physiology (2015)
    MD
    Charite University Medical Center Berlin, Medicine (2012)

    Research

    Overview

    Anesthesia is applied neuroscience, and neuroscience uses anesthesia as a powerful experimental probe to understand how brain networks give rise to consciousness—and how disrupting those networks alters cognition and behavior.

    The Helfrich Lab investigates the neurophysiology of unconscious states and their consequences for human cognition, using primarily scalp electroencephalography (EEG) to characterize shared and state-specific neural mechanisms across anesthesia, sleep, and disorders of consciousness.

    Our work asks whether anesthesia can be re-engineered to more closely resemble sleep rather than coma, thereby reducing postoperative cognitive side effects while potentially harnessing sleep’s restorative functions, and whether anesthetic perturbations can serve as diagnostic probes to predict recovery trajectories in patients with coma or other disorders of consciousness. The overarching goal of this research is to translate mechanistic insights into improved clinical care for all patients.

    Medical Research Interests

    Anesthesia; Consciousness; Electroencephalography; Neurosciences; Sleep

    Research at a Glance

    Yale Co-Authors

    Frequent collaborators of Janna D Helfrich's published research.

    Publications

    2026

    2025

    2024

    2023

    Academic Achievements & Community Involvement

    Honors

    • honor

      WAKWin Mentorship Award

    • honor

      Travel Grant

    • honor

      Travel Grant

    • honor

      Travel Grant

    • honor

      Travel Grant

    Clinical Care

    Overview

    Janna D. Helfrich, MD, is an anesthesiologist who cares for adults before, during, and after surgery. She focuses on providing safe anesthesia care and supporting patients through all phases of their surgical experience.

    Dr. Helfrich cares for patients with a wide range of medical conditions who need anesthesia for surgery or procedures. She monitors vital signs such as blood pressure, heart rate, and breathing, and adjusts anesthesia medications to keep patients comfortable and safe. She also has training in intensive care and prehospital emergency care, which helps her manage patients who are critically ill or at higher risk during surgery.

    As an assistant professor at Yale School of Medicine, Dr. Helfrich studies how anesthesia affects the brain and consciousness. Her research uses brainwave recordings, called EEG, to compare anesthesia with natural sleep and with conditions such as coma. She aims to better understand how changes in brain activity under anesthesia may affect thinking and memory after surgery, and how this knowledge can be used to improve patient care.

    Dr. Helfrich earned her medical degree and a medical doctorate from Charite University Medical Center Berlin. She completed residency training in anesthesiology at University Medical Center Tuebingen and University Medical Center Hamburg-Eppendorf, all in Germany. She also pursued fellowship training in prehospital emergency care and intensive care medicine at University Medical Center Hamburg-Eppendorf, and a postdoctoral fellowship in neuroscience at the University of California at Berkeley.

    Clinical Specialties

    Anesthesiology

    Board Certifications

    • Anesthesiology

      Certification Organization
      German Board Certificate
      Original Certification Date
      2022

    Get In Touch

    Contacts

    Mailing Address

    Yale School of Medicine

    333 Cedar St, Dept of Anesthesiology

    New Haven, CT 06510

    United States

    Locations

    • Brady Memorial Laboratory

      Lab

      310 Cedar Street, Fl 4, Rm 419

      New Haven, CT 06510

    • Patient Care Locations

      Are You a Patient? View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.