2015
Effect of drugs on the risk of injuries in children with attention deficit hyperactivity disorder: a prospective cohort study
Dalsgaard S, Leckman JF, Mortensen PB, Nielsen HS, Simonsen M. Effect of drugs on the risk of injuries in children with attention deficit hyperactivity disorder: a prospective cohort study. The Lancet Psychiatry 2015, 2: 702-709. PMID: 26249301, DOI: 10.1016/s2215-0366(15)00271-0.Peer-Reviewed Original ResearchConceptsAge 10 yearsAttention deficit hyperactivity disorderAge 12 yearsRisk of injuryPrevalence of injuriesCommon causeDeficit hyperactivity disorderPharmacological treatmentEmergency wardOdds ratioADHD drugsMajor public health importanceEmergency ward visitsHyperactivity disorderProspective cohort studyDanish national registersNon-treated childrenLarge disease burdenPublic health importanceEffects of drugsCohort studyWard visitsUntreated childrenAdjusted differenceDisease burden
2014
Meta-analysis: hoarding symptoms associated with poor treatment outcome in obsessive–compulsive disorder
Bloch MH, Bartley CA, Zipperer L, Jakubovski E, Landeros-Weisenberger A, Pittenger C, Leckman JF. Meta-analysis: hoarding symptoms associated with poor treatment outcome in obsessive–compulsive disorder. Molecular Psychiatry 2014, 19: 1025-1030. PMID: 24912494, PMCID: PMC4169729, DOI: 10.1038/mp.2014.50.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderTreatment responseOCD patientsOdds ratioFurther treatment researchCase-control studyPoor treatment outcomesDifferential treatment responseSymptoms of OCDPrimary outcomeTreatment modalitiesEligible studiesTreatment outcomesPatientsElectronic searchSymptomsTotal participantsBehavioral therapyOCD treatmentDisordersSymptom dimensionsTreatment researchDSM-5Hoarding symptomsTreatment
2010
Severe psychosocial stress and heavy cigarette smoking during pregnancy: an examination of the pre- and perinatal risk factors associated with ADHD and Tourette syndrome
Motlagh MG, Katsovich L, Thompson N, Lin H, Kim YS, Scahill L, Lombroso PJ, King RA, Peterson BS, Leckman JF. Severe psychosocial stress and heavy cigarette smoking during pregnancy: an examination of the pre- and perinatal risk factors associated with ADHD and Tourette syndrome. European Child & Adolescent Psychiatry 2010, 19: 755-764. PMID: 20532931, PMCID: PMC3932440, DOI: 10.1007/s00787-010-0115-7.Peer-Reviewed Original ResearchConceptsHeavy maternal smokingPerinatal risk factorsAttention-deficit/hyperactivity disorderSevere psychosocial stressRisk factorsMaternal smokingTourette syndromePsychosocial stressUnaffected control childrenControl childrenHeavy cigarette smokingHigh-risk populationStatistical significanceDiagnosis of ADHDComorbid Tourette's syndromeHigh rateMothers of childrenMaternal report dataHeavy smokingPerinatal historyCigarette smokingOdds ratioPsychiatric assessmentSmokingStandardized questionnaire