2023
Utility of promoter hypermethylation in malignant risk stratification of intraductal papillary mucinous neoplasms
Chhoda A, Sharma A, Sailo B, Tang H, Ruzgar N, Tan W, Ying L, Khatri R, Narayanan A, Mane S, De Kumar B, Wood L, Iacobuzio-Donahue C, Wolfgang C, Kunstman J, Salem R, Farrell J, Ahuja N. Utility of promoter hypermethylation in malignant risk stratification of intraductal papillary mucinous neoplasms. Clinical Epigenetics 2023, 15: 28. PMID: 36803844, PMCID: PMC9942382, DOI: 10.1186/s13148-023-01429-5.Peer-Reviewed Original ResearchConceptsPapillary mucinous neoplasmMalignant risk stratificationCACNA1G geneRisk stratificationMucinous neoplasmsBiomarker panelBackgroundIntraductal papillary mucinous neoplasmIntraductal papillary mucinous neoplasmEarly detectionPrevious case-control studyHigh-grade dysplasiaCase-control studyPancreatic cancer precursorsReceiver Operating Characteristic (ROC) curve analysisSignificant diagnostic challengeCross-sectional imagingCharacteristic curve analysisOperating Characteristic curve analysisG geneHigh diagnostic specificityPrior validation studiesSignificant procedural riskIPMN tissuesSurgical resectionAdvanced neoplasia
2016
Detection of Advanced Neoplasia in Pancreatic Cysts by Assay of Novel DNA Methylation Markers in Cyst Fluid: A Multicenter Pilot Study: 2016 ACG Fellows-In-Training Award (Biliary/Pancreas Category)
Majumder S, Taylor W, Yab T, Berger C, Mahoney D, Aslanian H, Farrell J, Fisher W, Rothberg B, Salem R, Simeone D, Van Buren G, Raimondo M, Chari S, Kisiel J, Topazian M, Ahlquist D. Detection of Advanced Neoplasia in Pancreatic Cysts by Assay of Novel DNA Methylation Markers in Cyst Fluid: A Multicenter Pilot Study: 2016 ACG Fellows-In-Training Award (Biliary/Pancreas Category). The American Journal Of Gastroenterology 2016, 111: s1. DOI: 10.14309/00000434-201610001-00002.Peer-Reviewed Original Research