2010
Early Pharmacokinetic and Pharmacodynamic Effects of Mixing Lispro With Glargine Insulin Results of glucose clamp studies in youth with type 1 diabetes
Cengiz E, Tamborlane WV, Martin-Fredericksen M, Dziura J, Weinzimer SA. Early Pharmacokinetic and Pharmacodynamic Effects of Mixing Lispro With Glargine Insulin Results of glucose clamp studies in youth with type 1 diabetes. Diabetes Care 2010, 33: 1009-1012. PMID: 20150302, PMCID: PMC2858163, DOI: 10.2337/dc09-2118.Peer-Reviewed Original ResearchConceptsType 1 diabetesGlucose clamp studiesGlucose excursionsClamp studiesMeal-related glucose excursionsRapid-acting insulin analoguesRapid-acting insulinEuglycemic glucose clampTime-action curvePharmacodynamic peakA1c levelsTreatment burdenPharmacodynamic effectsDaily injectionsUnits/Pharmacodynamic actionClinical studiesGlucose clampMixed injectionGlargineEarly pharmacokineticsInsulin analoguesObjective clinicianInsulin pharmacokineticsLispro
2006
Effects of Simvastatin and Oral Contraceptive Agent on Polycystic Ovary Syndrome: Prospective, Randomized, Crossover Trial
Banaszewska B, Pawelczyk L, Spaczynski RZ, Dziura J, Duleba AJ. Effects of Simvastatin and Oral Contraceptive Agent on Polycystic Ovary Syndrome: Prospective, Randomized, Crossover Trial. The Journal Of Clinical Endocrinology & Metabolism 2006, 92: 456-461. PMID: 17105841, DOI: 10.1210/jc.2006-1988.Peer-Reviewed Original ResearchConceptsOral contraceptive pillsPolycystic ovary syndromeLow-density lipoprotein cholesterolTotal testosteroneLipoprotein cholesterolOvary syndromeSystemic inflammationCrossover trialSoluble vascular cell adhesion molecule-1Treatment of PCOSVascular cell adhesion molecule-1Ovarian theca-interstitial cellsCell adhesion molecule-1Oral contraceptive agentsSerum total testosteronePrimary outcome measureC-reactive proteinEffect of simvastatinTheca-interstitial cellsAdhesion molecule-1Academic medical centerRandom-effects modelCardiovascular riskFree testosteroneTotal cholesterol