2022
Association of renalase with clinical outcomes in hospitalized patients with COVID-19
Safdar B, Wang M, Guo X, Cha C, Chun HJ, Deng Y, Dziura J, El-Khoury JM, Gorelick F, Ko AI, Lee AI, Safirstein R, Simonov M, Zhou B, Desir GV. Association of renalase with clinical outcomes in hospitalized patients with COVID-19. PLOS ONE 2022, 17: e0264178. PMID: 35259186, PMCID: PMC8903289, DOI: 10.1371/journal.pone.0264178.Peer-Reviewed Original ResearchConceptsCOVID-19 patientsRenalase levelsIntensive care unit admissionHospitalized COVID-19 patientsMean age 64 yearsCOVID-19Cox proportional hazards modelCare unit admissionPrimary composite outcomeRetrospective cohort studyUse of vasopressorsSevere COVID-19IL-6 levelsAge 64 yearsRisk of deathCOVID-19 subjectsInitial disease severityProportional hazards modelCOVID-19 diseasePlasma renalaseUnit admissionICU admissionCohort studyComposite outcomeCytokine levels
2020
All-cause mortality among males living with and without HIV initiating long-term opioid therapy, and its association with opioid dose, opioid interruption and other factors
Gordon K, Manhapra A, Crystal S, Dziura J, Edelman E, Skanderson M, Kerns R, Justice A, Tate J, Becker W. All-cause mortality among males living with and without HIV initiating long-term opioid therapy, and its association with opioid dose, opioid interruption and other factors. Drug And Alcohol Dependence 2020, 216: 108291. PMID: 33011662, PMCID: PMC7644145, DOI: 10.1016/j.drugalcdep.2020.108291.Peer-Reviewed Original ResearchConceptsMorphine equivalent daily doseCause mortalityLong-term opioid therapyTime-updated Cox regressionStrong dose-response relationshipUnnatural deathsEquivalent daily doseDose-response relationshipOpioid doseOpioid therapyUninfected patientsOpioid useDaily doseCox regressionMortality outcomesTherapy doseHigh doseMale veteransOverdose fatalitiesOverdose mortalityPLWHMortalityHIVPatientsDose
2017
Incident Cardiovascular Risk Factors Among Men and Women Veterans After Return From Deployment
Haskell SG, Brandt C, Burg M, Bastian L, Driscoll M, Goulet J, Mattocks K, Dziura J. Incident Cardiovascular Risk Factors Among Men and Women Veterans After Return From Deployment. Medical Care 2017, 55: 948-955. PMID: 28984707, DOI: 10.1097/mlr.0000000000000801.Peer-Reviewed Original ResearchConceptsCardiovascular risk factorsCV risk factorsRisk factorsImpact of sexWomen veteransClinical Modification diagnostic codesIncident cardiovascular risk factorsPrimary care visitsCoronary artery diseaseElectronic health record dataRisk of obesityVeterans Health AdministrationIncident risk factorsHealth record dataMental health conditionsBlack womenNew International ClassificationCare visitsCohort studyArtery diseaseFemale sexDiagnostic codesIncidence rateProtective effectInternational Classification
2014
Impact of Early Extubation and Reintubation on the Incidence of Bronchopulmonary Dysplasia in Neonates
Berger J, Mehta P, Bucholz E, Dziura J, Bhandari V. Impact of Early Extubation and Reintubation on the Incidence of Bronchopulmonary Dysplasia in Neonates. American Journal Of Perinatology 2014, 31: 1063-1072. PMID: 24683068, DOI: 10.1055/s-0034-1371702.Peer-Reviewed Original ResearchMeSH KeywordsAirway ExtubationApgar ScoreBirth WeightBronchopulmonary DysplasiaDisease-Free SurvivalDuctus Arteriosus, PatentFemaleGestational AgeHumansIncidenceInfant, NewbornIntracranial HemorrhagesIntubation, IntratrachealKaplan-Meier EstimateMaleProportional Hazards ModelsRespiratory Distress Syndrome, NewbornRetinopathy of PrematurityRetreatmentRetrospective StudiesTime Factors
2005
Cyclin D1 Is a Valuable Prognostic Marker in Oropharyngeal Squamous Cell Carcinoma
Yu Z, Weinberger PM, Haffty BG, Sasaki C, Zerillo C, Joe J, Kowalski D, Dziura J, Camp RL, Rimm DL, Psyrri A. Cyclin D1 Is a Valuable Prognostic Marker in Oropharyngeal Squamous Cell Carcinoma. Clinical Cancer Research 2005, 11: 1160-1166. PMID: 15709184, DOI: 10.1158/1078-0432.1160.11.3.Peer-Reviewed Original ResearchConceptsOropharyngeal squamous cell carcinomaDisease-free survivalSquamous cell carcinomaCyclin D1Overall survivalCell carcinomaPrognostic markerOropharyngeal squamous cell cancerProtein expressionLocal recurrence rateMultivariate Cox regressionLong-term followSquamous cell cancerCyclin D1 expression levelsNuclear cyclin D1 expressionTerms of prognosisCell cycle regulator cyclin D1Valuable prognostic markerExpression levelsCyclin D1 expressionProtein expression levelsMean followIndependent predictorsLocal recurrenceCell cancer