2019
Results of a pilot/phase II study of gamma knife radiosurgery for brain metastases and implications for future prospective clinical trials
Yu J, Singh C, Bindra R, Contessa J, Husain Z, Hansen J, Park H, Roberts K, Bond J, Tien C, Guo F, Colaco R, Housri N, Magnuson W, Mahajan A, Omay S, Chiang V. Results of a pilot/phase II study of gamma knife radiosurgery for brain metastases and implications for future prospective clinical trials. Journal Of Radiation Oncology 2019, 8: 39-46. DOI: 10.1007/s13566-018-0370-7.Peer-Reviewed Original ResearchYale-New Haven HospitalPhase II studyBrain metastasesClinical trialsII studyKnife radiosurgeryLocal controlPre-defined primary endpointWhole-brain radiation treatmentFuture prospective clinical trialsEvaluable brain metastasesSymptomatic radiation necrosisMedian patient ageLocal control ratePhase 2 studyGood local controlProspective clinical trialsNumber of metastasesLarge clinical trialsProportional hazards regressionFuture clinical trialsGamma knife radiosurgeryImportant clinical variablesStandard clinical practiceNew Haven Hospital
2018
A Pilot/Phase II Study of Stereotactic Radiosurgery for Brain Metastases Using Rational Dose Selection
Yu J, Singh C, Bindra R, Contessa J, Husain Z, Hansen J, Park H, Roberts K, Bond J, Tien C, Guo F, Colaco R, Housri N, Magnuson W, Omay B, Chiang V. A Pilot/Phase II Study of Stereotactic Radiosurgery for Brain Metastases Using Rational Dose Selection. International Journal Of Radiation Oncology • Biology • Physics 2018, 102: e372-e373. DOI: 10.1016/j.ijrobp.2018.07.1113.Peer-Reviewed Original Research
2014
BM-10SYSTEMIC TREATMENT AND RADIATION NECROSIS FOLLOWING GKSRS IN THE TREATMENT OF BRAIN METASTASES
Colaco R, Martin P, Bond J, Bindra R, Contessa J, Kluger H, Yu J, Chiang V. BM-10SYSTEMIC TREATMENT AND RADIATION NECROSIS FOLLOWING GKSRS IN THE TREATMENT OF BRAIN METASTASES. Neuro-Oncology 2014, 16: v34-v34. PMCID: PMC4217910, DOI: 10.1093/neuonc/nou240.10.Peer-Reviewed Original ResearchSystemic Treatment and Radiation Necrosis Following Gamma Knife Radiosurgery in the Treatment of Brain Metastases
Colaco R, Martin P, Bond J, Bindra R, Contessa J, Kluger H, Yu J, Chiang V. Systemic Treatment and Radiation Necrosis Following Gamma Knife Radiosurgery in the Treatment of Brain Metastases. International Journal Of Radiation Oncology • Biology • Physics 2014, 90: s310. DOI: 10.1016/j.ijrobp.2014.05.1035.Peer-Reviewed Original Research
2006
Multivariate analysis identifies factors that affect survival after stereotactic radiosurgery for brain metastases
Diluna M, King J, Knisely J, Bond J, De Lotbiniere A, Chiang V. Multivariate analysis identifies factors that affect survival after stereotactic radiosurgery for brain metastases. Journal Of Clinical Oncology 2006, 24: 11500-11500. DOI: 10.1200/jco.2006.24.18_suppl.11500.Peer-Reviewed Original ResearchCell lung carcinomaStereotactic radiosurgeryBrain metastasesCerebral metastasesSurgical resectionEsophageal cancerLung carcinomaBreast cancerNon-small cell lung carcinomaSmall cell lung carcinomaSystemic controlConnecticut Tumor RegistryLocation of metastasesNumber of metastasesPatient-related factorsTotal tumor burdenSystemic disease controlKaplan-Meier plotsSignificant independent predictorsSurvival dataTotal tumor volumeMedian survivalWorse survivalImproved survivalIndependent predictors