Analysis of pathologic extent of disease for clinically localized prostate cancer after radical prostatectomy and subsequent use of adjuvant radiation in a national cohort
Schreiber D, Rineer J, Yu J, Olsheski M, Nwokedi E, Schwartz D, Choi K, Rotman M. Analysis of pathologic extent of disease for clinically localized prostate cancer after radical prostatectomy and subsequent use of adjuvant radiation in a national cohort. Cancer 2010, 116: 5757-5766. PMID: 20737571, DOI: 10.1002/cncr.25561.Peer-Reviewed Original ResearchConceptsProstate-specific antigenClinically localized prostate cancerPositive surgical marginsLocalized prostate cancerAdjuvant radiationRadical prostatectomySurgical marginsProstate cancerPathologic extentRate of organ-confined diseaseProstate-specific antigen levelRisk of extraprostatic extensionPatterns of care studyOrgan-confined diseaseNegative surgical marginsEnd Results databaseLogistic regression analysisPopulation-based studyExtraprostatic diseaseExtraprostatic extensionGleason 7Gleason 8Postoperative radiationProstatic adenocarcinomaResults database