2012
Tumorigenic and Prognostic Significance of RASSF1A Expression in Low-grade (WHO Grade 1 and Grade 2) Nonmuscle-invasive Bladder Cancer
Ha Y, Jeong P, Kim J, Kwon W, Kim I, Yun S, Kim G, Choi Y, Moon S, Kim W. Tumorigenic and Prognostic Significance of RASSF1A Expression in Low-grade (WHO Grade 1 and Grade 2) Nonmuscle-invasive Bladder Cancer. Urology 2012, 79: 1411.e1-1411.e6. PMID: 22446336, DOI: 10.1016/j.urology.2012.01.042.Peer-Reviewed Original ResearchConceptsLow-grade nonmuscle-invasive bladder cancersNonmuscle invasive bladder cancerPolymerase chain reactionBladder cancerTumor tissueMultivariate Cox regression analysisMRNA expressionTissue levelsRASSF1A expressionCox regression analysisKaplan-Meier estimatesChain reactionNormal bladder mucosaTumor tissue levelsNormal tissue levelsReal-time polymerase chain reactionRASSF1A promoter methylationQuantitative real-time polymerase chain reactionMethylation-specific polymerase chain reactionEffect of RASSF1AT ratioIndependent predictorsPrognostic significancePrognostic valueLarge tumors
2010
Tissue hOGG1 Genotype Predicts Bladder Cancer Prognosis: A Novel Approach Using a Peptide Nucleic Acid Clamping Method
Ha Y, Yan C, Kim I, Yun S, Moon S, Kim W. Tissue hOGG1 Genotype Predicts Bladder Cancer Prognosis: A Novel Approach Using a Peptide Nucleic Acid Clamping Method. Annals Of Surgical Oncology 2010, 18: 1775-1781. PMID: 21184188, DOI: 10.1245/s10434-010-1500-7.Peer-Reviewed Original ResearchConceptsMuscle-invasive bladder cancerBladder cancerPolymerase chain reactionNonmuscle invasive bladder cancer patientsHOGG1 codon 326 genotypesProgression-free survival benefitInvasive bladder cancer patientsTumor tissueTissue genotypeHOGG1 codon 326Primary BC patientsCox regression analysisInvasive bladder cancerBladder cancer prognosisPrimary bladder cancerAggressive clinicopathological featuresBladder cancer patientsReal-time polymerase chain reactionSurvival benefitBC prognosisClinicopathological characteristicsClinicopathological featuresBC patientsPrognostic indicatorCancer patients