1995
Hypopigmented variant of mycosis fungoides: Demography, histopathology, and treatment of seven cases
Lambroza E, Cohen S, Phelps R, Lebwohl M, Braverman I, DiCostanzo D. Hypopigmented variant of mycosis fungoides: Demography, histopathology, and treatment of seven cases. Journal Of The American Academy Of Dermatology 1995, 32: 987-993. PMID: 7751470, DOI: 10.1016/0190-9622(95)91337-8.Peer-Reviewed Original ResearchConceptsMycosis fungoidesEpidermal atrophyVariant of MFTreatment of choiceMedian ageMononuclear cellsHistologic findingsBiopsy diagnosisComplete repigmentationDisease onsetTreatment outcomesMF variantDisease processNew casesYoung populationPrior reportsFungoidesPUVAPatientsAtrophyMicroscopic featuresHistopathologyTreatmentDark skinSkin
1992
Human dermatosparaxis: a form of Ehlers-Danlos syndrome that results from failure to remove the amino-terminal propeptide of type I procollagen.
Smith L, Wertelecki W, Milstone L, Petty E, Seashore M, Braverman I, Jenkins T, Byers P. Human dermatosparaxis: a form of Ehlers-Danlos syndrome that results from failure to remove the amino-terminal propeptide of type I procollagen. American Journal Of Human Genetics 1992, 51: 235-44. PMID: 1642226, PMCID: PMC1682688.Peer-Reviewed Original ResearchConceptsAmino-terminal propeptideFragile skinType IConnective tissue disordersEhlers-Danlos syndromeLax jointsType VIIAffected animalsSkinChildrenCultured fibroblastsNormal cellsEhlers-Danlos syndrome type VIIPro alphaDisordersPropeptideAlphaDermatosparaxisProteolytic processingSepsisN-proteinaseCellsSyndromeCollagen fibrils
1989
Skin changes in menopause
Bolognia J, Braverman I, Rousseau M, Sarrel P. Skin changes in menopause. Maturitas 1989, 11: 295-304. PMID: 2693917, DOI: 10.1016/0378-5122(89)90026-1.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsMenopausal womenEstrogen replacement therapyElastic fibersAge-related ultrastructural changesSun-exposed skinSun-protected skinDermal elastic fibersCutaneous signsEstrogen deprivationPremature menopauseReplacement therapySkin changesSkin signsTreatment periodCystic spacesDegenerative changesGranular degenerationSymptomsUltrastructural changesWomenMenopauseSignificant differencesPatientsPremature agingSkinAngiogenic properties of normal and psoriatic skin associate with epidermis, not dermis.
Malhotra R, Stenn K, Fernandez L, Braverman I. Angiogenic properties of normal and psoriatic skin associate with epidermis, not dermis. Laboratory Investigation 1989, 61: 162-5. PMID: 2474089.Peer-Reviewed Original ResearchConceptsPsoriatic patientsPsoriatic plaque skinInflammatory cellsVascular proliferationPsoriatic lesionsPsoriatic skinNormal subjectsSkin diseasesDay 2Nonpsoriatic skinNormal skinPatient's skinAngiogenic activityAngiogenic stimuliVessel growthAngiogenic propertiesDermisNew vesselsAngiogenic assaysSkinPsoriasisVessel formationPatientsEpidermal growthLesionsElastic Fiber and Microvascular Abnormalities in Aging Skin
Braverman I. Elastic Fiber and Microvascular Abnormalities in Aging Skin. Clinics In Geriatric Medicine 1989, 5: 69-90. PMID: 2646003, DOI: 10.1016/s0749-0690(18)30696-7.Peer-Reviewed Original ResearchConceptsMicrovascular abnormalitiesSpecific clinical featuresElastic fiber abnormalitiesClinical featuresDiabetic patientsVeil cellsJuvenile diabetesDiabetic skinFiber abnormalitiesMajor manifestationsIdentical abnormalitiesCutaneous agingAbnormalitiesCutaneous laxitySkinElastic fibersFunctional stateElastic fiber networkWall alterationsAlterationsAging processLikely correlateDiabetesPatientsAtrophy
1987
Electron microscopic and immunolabeling studies of the lesional and normal skin of patients with mycosis fungoides treated by total body electron beam irradiation
Braverman I, Klein S, Grant A. Electron microscopic and immunolabeling studies of the lesional and normal skin of patients with mycosis fungoides treated by total body electron beam irradiation. Journal Of The American Academy Of Dermatology 1987, 16: 61-74. PMID: 3100584, DOI: 10.1016/s0190-9622(87)70005-x.Peer-Reviewed Original ResearchConceptsEpidermal Langerhans cellsElectron beam therapyLangerhans cellsMycosis fungoidesIndeterminate cellsNormal skinDisease courseLesional skinBeam therapySkin lesionsNonspecific skin lesionsPatient's disease courseIa-positive cellsEpidermal cell suspensionsEpidermal thymocyteClinical remissionBiopsy specimensPretreatment levelsIa antigensFungoidesTherapyLesionsSkinPatientsCells
1986
Elastic Fiber and Microvascular Abnormalities in Aging Skin
Braverman I. Elastic Fiber and Microvascular Abnormalities in Aging Skin. Dermatologic Clinics 1986, 4: 391-405. PMID: 3521985, DOI: 10.1016/s0733-8635(18)30802-7.Peer-Reviewed Original ResearchConceptsMicrovascular abnormalitiesSpecific clinical featuresElastic fiber abnormalitiesDiabetic patientsJuvenile diabeticsClinical featuresVeil cellsDiabetic skinFiber abnormalitiesMajor manifestationsIdentical abnormalitiesCutaneous agingAbnormalitiesCutaneous laxitySkinElastic fibersFunctional stateElastic fiber networkWall alterationsAlterationsAging processDiabeticsLikely correlatePatientsAtrophy
1984
Ultrastructural Abnormalities of the Microvasculature and Elastic Fibers in the Skin of Juvenile Diabetics
Braverman I, Keh-Yen A. Ultrastructural Abnormalities of the Microvasculature and Elastic Fibers in the Skin of Juvenile Diabetics. Journal Of Investigative Dermatology 1984, 82: 270-274. PMID: 6699427, DOI: 10.1111/1523-1747.ep12260279.Peer-Reviewed Original ResearchConceptsElastic fiber abnormalitiesJuvenile diabeticsFiber abnormalitiesVascular wallUnderlying metabolic derangementsBasement membrane-like materialMetabolic derangementsIndividuals 50Buttock skinDiabetic skinPeripheral depositionUltrastructural abnormalitiesMembrane-like materialAbnormalitiesDiabeticsBasement membraneSkinElastic fibers
1982
Studies in Cutaneous Aging II. The Microvasculature
Braverman I, Fonferko E. Studies in Cutaneous Aging II. The Microvasculature. Journal Of Investigative Dermatology 1982, 78: 444-448. PMID: 7069222, DOI: 10.1111/1523-1747.ep12508027.Peer-Reviewed Original ResearchConceptsVeil cellsBasement membrane-like materialButtock skinVascular wallMicrocirculatory vesselsMembrane-like materialVascular wall thickeningThin-walled vesselsDiabetes mellitusAging IIActinic damagePsoriatic individualsIndividuals 80Chronological agingPostcapillary venulesWall thickeningPeripheral portionVenous capillariesProgressive agingSkinRough endoplasmic reticulumEarly phaseWalled vesselsVesselsCellsStudies in Cutaneous Aging: I. The Elastic Fiber Network
Braverman I, Fonferko E. Studies in Cutaneous Aging: I. The Elastic Fiber Network. Journal Of Investigative Dermatology 1982, 78: 434-443. PMID: 7069221, DOI: 10.1111/1523-1747.ep12507866.Peer-Reviewed Original ResearchConceptsButtock skinActinic damageCutaneous agingElastic fibersElastic fiber degradationInflammatory cellsAge 50Age 70Psoriatic individualsChronological agingAge 30Young adultsPorcine pancreatic elastaseAbnormalitiesSkinPancreatic elastaseElastaseElastic fiber networkDifferent agesAgingMorphological evidenceDamageRole of the Microcirculation in the Treatment and Pathogenesis of Psoriasis
Braverman I, Sibley J. Role of the Microcirculation in the Treatment and Pathogenesis of Psoriasis. Journal Of Investigative Dermatology 1982, 78: 12-17. PMID: 7054305, DOI: 10.1111/1523-1747.ep12497850.Peer-Reviewed Original ResearchConceptsLabeling indexCapillary loopsButtock skinPathogenesis of psoriasisNormal labeling indexUntreated patientsPsoriatic patientsPUVA treatmentSerial biopsiesVascular proliferationEpidermal hyperplasiaAbnormal capillariesPatientsPsoriasisBasal cellsCapillary growthIndividual plaquesArterial capillariesBiopsyTreatmentSkinIdentical methodsDay intervalsPsoriaticsCapillaries
1975
Demonstration of Immune Complexes in Spontaneous and Histamine-Induced Lesions and in Normal Skin of Patients with Leukocytoclastic Angiitis
Braverman I, Yen A. Demonstration of Immune Complexes in Spontaneous and Histamine-Induced Lesions and in Normal Skin of Patients with Leukocytoclastic Angiitis. Journal Of Investigative Dermatology 1975, 64: 105-112. PMID: 123546, DOI: 10.1111/1523-1747.ep12510321.Peer-Reviewed Original ResearchConceptsHistamine-induced whealElectron-dense depositsImmune complexesUninvolved skinSpontaneous lesionsDirect immunofluorescenceImmune reactantsImmune complex pathogenesisImmune complex diseaseVessel wallLeukocytoclastic angiitisHistopathologic changesComplex pathogenesisLocal injectionNormal skinPostcapillary venulesLesionsPatientsWhealDamage ensuesImmunofluorescenceAngitisSkinNeutrophilsHistamine