Clinical presentation of hereditary angioedema.
Azmy V, Brooks JP, Hsu FI. Clinical presentation of hereditary angioedema. Allergy & Asthma Proceedings 2020, 41: s18-s21. PMID: 33109320, DOI: 10.2500/aap.2020.41.200065.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsHereditary angioedemaHAE attacksSevere abdominal painHalf of patientsAutosomal dominant diseaseC1 inhibitor proteinLaryngeal angioedemaOropharyngeal swellingAbdominal attacksAbdominal painErythema marginatumSignificant hypotensionLaryngeal edemaPrompt diagnosisClinical presentationMinor traumaSignificant morbiditySubmucosal edemaBowel soundsPhysical examinationRecurrent episodesGenitourinary tractFrequent precipitantUnpredictable severityVariable presentation