On high-dimensional misspecified mixed model analysis in genome-wide association study
Jiang J, Li C, Paul D, Yang C, Zhao H. On high-dimensional misspecified mixed model analysis in genome-wide association study. The Annals Of Statistics 2016, 44: 2127-2160. DOI: 10.1214/15-aos1421.Peer-Reviewed Original ResearchREML estimatorsAsymptotic resultsAsymptotic conditional varianceReal data applicationRandom effectsMaximum likelihood estimatorExtensive simulation studyAsymptotic analysisConvergence rateLikelihood estimatorLinear mixed modelsEstimatorSimulation studyConvergenceData applicationsTrue varianceConditional varianceImportant genetic implicationsCertain limits