2011
Recruitment of Endophilin to Clathrin-Coated Pit Necks Is Required for Efficient Vesicle Uncoating after Fission
Milosevic I, Giovedi S, Lou X, Raimondi A, Collesi C, Shen H, Paradise S, O'Toole E, Ferguson S, Cremona O, De Camilli P. Recruitment of Endophilin to Clathrin-Coated Pit Necks Is Required for Efficient Vesicle Uncoating after Fission. Neuron 2011, 72: 587-601. PMID: 22099461, PMCID: PMC3258500, DOI: 10.1016/j.neuron.2011.08.029.Peer-Reviewed Original Research
2010
Constitutive activated Cdc42-associated kinase (Ack) phosphorylation at arrested endocytic clathrin-coated pits of cells that lack dynamin
Shen H, Ferguson SM, Dephoure N, Park R, Yang Y, Volpicelli-Daley L, Gygi S, Schlessinger J, De Camilli P. Constitutive activated Cdc42-associated kinase (Ack) phosphorylation at arrested endocytic clathrin-coated pits of cells that lack dynamin. Molecular Biology Of The Cell 2010, 22: 493-502. PMID: 21169560, PMCID: PMC3038647, DOI: 10.1091/mbc.e10-07-0637.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCdc42 GTP-Binding ProteinCell LineChlorocebus aethiopsClathrinClathrin Heavy ChainsClathrin Light ChainsCoated Pits, Cell-MembraneCOS CellsDynamin IDynamin IIEndocytosisFibroblastsGene Knockout TechniquesHumansMiceMice, KnockoutPhosphorylationProtein BindingProtein-Tyrosine KinasesSignal TransductionConceptsEndocytic clathrin-coated pitsClathrin-coated pitsRNA interference-based approachesFundamental cellular processesGrowth factor receptor signalingWild-type cellsNonreceptor tyrosine kinaseActive Cdc42Cellular processesSpecific cargoClathrin assemblyEndocytic routeEndocytic vesiclesGrowth factor receptorTyrosine phosphorylationPhosphorylation stateClathrin boxTyrosine kinaseKinase phosphorylationCdc42Receptor signalingActivation-deactivation cyclePhosphorylationDynaminFactor receptor
2009
Coordinated Actions of Actin and BAR Proteins Upstream of Dynamin at Endocytic Clathrin-Coated Pits
Ferguson S, Raimondi A, Paradise S, Shen H, Mesaki K, Ferguson A, Destaing O, Ko G, Takasaki J, Cremona O, Toole E, De Camilli P. Coordinated Actions of Actin and BAR Proteins Upstream of Dynamin at Endocytic Clathrin-Coated Pits. Developmental Cell 2009, 17: 811-822. PMID: 20059951, PMCID: PMC2861561, DOI: 10.1016/j.devcel.2009.11.005.Peer-Reviewed Original ResearchMeSH KeywordsActinsAnimalsCell MembraneClathrinCoated Pits, Cell-MembraneCytoskeletonDynamin IDynamin IIEndocytosisGene Knockout TechniquesMiceMice, KnockoutConceptsEndocytic roleEndocytic clathrin-coated pitsBAR domain proteinsSense membrane curvatureClathrin-coated pitsWild-type cellsGTPase dynaminEndocytic intermediatesHigher eukaryotesDomain proteinsMembrane fissionActin dynamicsNumerous proteinsDynaminMembrane curvatureProtein upstreamTubular neckConcerted actionProteinActinCoordinated actionKey playersFunctional relationshipCellsSequence of events