2018
Whole genome association study of brain‐wide imaging phenotypes: A study of the ping cohort
Wen C, Mehta CM, Tan H, Zhang H. Whole genome association study of brain‐wide imaging phenotypes: A study of the ping cohort. Genetic Epidemiology 2018, 42: 265-275. PMID: 29411414, PMCID: PMC5851842, DOI: 10.1002/gepi.22111.Peer-Reviewed Original ResearchConceptsGenetic markersGenome-wide association study datasetWhole-genome association studiesComplex genetic basisGenome association studiesBrain-wide imaging phenotypesMultivariate phenotypesGenetic basisAssociation studiesGenetic studiesNeuropsychological disordersClinical diagnostic criteriaCovariance testBiological basisPhenotypeDiagnostic criteriaNeuroimaging biomarkersBrain functionBrain structuresPediatric imagingGWASImaging phenotypesDiffusion tensor
2015
Cluster analysis of spontaneous preterm birth phenotypes identifies potential associations among preterm birth mechanisms
Esplin MS, Manuck TA, Varner MW, Christensen B, Biggio J, Bukowski R, Parry S, Zhang H, Huang H, Andrews W, Saade G, Sadovsky Y, Reddy UM, Ilekis J. Cluster analysis of spontaneous preterm birth phenotypes identifies potential associations among preterm birth mechanisms. American Journal Of Obstetrics And Gynecology 2015, 213: 429.e1-429.e9. PMID: 26070700, PMCID: PMC4556543, DOI: 10.1016/j.ajog.2015.06.011.Peer-Reviewed Original ResearchConceptsSpontaneous preterm birthDecidual hemorrhagePlacental dysfunctionProspective case-control multicenter studyCase-control multicenter studyPremature membrane ruptureGroup of womenCommon biologic pathwaysMaternal comorbiditiesPreterm singletonsPreterm birthWeeks' gestationMulticenter studyMaternal stressSecondary analysisBiologic pathwaysFamilial factorsGenetic factorsWomenPhenotypic profileGestationInfectionMembrane ruptureCommon mechanismPhenotype
2006
Ascertainment adjustment in genetic studies of ordinal traits
Feng R, Zhang H. Ascertainment adjustment in genetic studies of ordinal traits. Human Genetics 2006, 119: 429-435. PMID: 16528520, DOI: 10.1007/s00439-006-0147-8.Peer-Reviewed Original ResearchDetection of Genes for Ordinal Traits in Nuclear Families and a Unified Approach for Association Studies
Zhang H, Wang X, Ye Y. Detection of Genes for Ordinal Traits in Nuclear Families and a Unified Approach for Association Studies. Genetics 2006, 172: 693-699. PMID: 16219774, PMCID: PMC1456175, DOI: 10.1534/genetics.105.049122.Peer-Reviewed Original ResearchConceptsSingle nucleotide polymorphismsQuantitative traitsOrdinal traitsTraditional linkage studiesGenomewide association analysisAssociation of genesDetection of genesGametic disequilibriumLoci existAssociation studiesAssociation analysisGenesLinkage disequilibriumTraitsComplex diseasesLinkage studiesGrowth-associated protein 43Protein 43DisequilibriumPolymorphismFamilyMarkersNuclear families
2005
Genetic Analysis Workshop 14: microsatellite and single-nucleotide polymorphism marker loci for genome-wide scans
Bailey-Wilson JE, Almasy L, de Andrade M, Bailey J, Bickeböller H, Cordell HJ, Daw EW, Goldin L, Goode EL, Gray-McGuire C, Hening W, Jarvik G, Maher BS, Mendell N, Paterson AD, Rice J, Satten G, Suarez B, Vieland V, Wilcox M, Zhang H, Ziegler A, MacCluer JW. Genetic Analysis Workshop 14: microsatellite and single-nucleotide polymorphism marker loci for genome-wide scans. BMC Genomic Data 2005, 6: s1. PMID: 16451554, PMCID: PMC1866841, DOI: 10.1186/1471-2156-6-s1-s1.Peer-Reviewed Original ResearchData mining
Cupples LA, Bailey J, Cartier KC, Falk CT, Liu K, Ye Y, Yu R, Zhang H, Zhao H. Data mining. Genetic Epidemiology 2005, 29: s103-s109. PMID: 16342179, DOI: 10.1002/gepi.20117.Peer-Reviewed Original Research
2002
Genomewide Scan of Hoarding in Sib Pairs in Which Both Sibs Have Gilles de la Tourette Syndrome
Zhang H, Leckman JF, Pauls DL, Tsai CP, Kidd KK, Campos MR, Genetics T. Genomewide Scan of Hoarding in Sib Pairs in Which Both Sibs Have Gilles de la Tourette Syndrome. American Journal Of Human Genetics 2002, 70: 896-904. PMID: 11840360, PMCID: PMC379118, DOI: 10.1086/339520.Peer-Reviewed Original ResearchAllelesBehavioral SymptomsChromosomes, HumanChromosomes, Human, Pair 17Chromosomes, Human, Pair 4Chromosomes, Human, Pair 5Gene FrequencyGenetic LinkageGenetic MarkersGenome, HumanHumansMatched-Pair AnalysisNuclear FamilyObsessive-Compulsive DisorderPhenotypeQuantitative Trait, HeritableSoftwareStatistics, NonparametricTourette Syndrome
2001
Tree‐Based Linkage and Association Analyses of Asthma
Zhang H, Tsai C, Yu C, Bonney G. Tree‐Based Linkage and Association Analyses of Asthma. Genetic Epidemiology 2001, 21: s317-s322. PMID: 11793691, DOI: 10.1002/gepi.2001.21.s1.s317.Peer-Reviewed Original Research
2000
Use of classification trees for association studies
Zhang H, Bonney G. Use of classification trees for association studies. Genetic Epidemiology 2000, 19: 323-332. PMID: 11108642, DOI: 10.1002/1098-2272(200012)19:4<323::aid-gepi4>3.0.co;2-5.Peer-Reviewed Original Research