Post-operative radiotherapy is associated with improved survival in esophageal cancer with positive surgical margins
Gao SJ, Park HS, Corso CD, Rutter CE, Khan SA, Johung KL. Post-operative radiotherapy is associated with improved survival in esophageal cancer with positive surgical margins. Journal Of Gastrointestinal Oncology 2017, 8: 953-961. PMID: 29299354, PMCID: PMC5750177, DOI: 10.21037/jgo.2017.08.12.Peer-Reviewed Original ResearchPost-operative radiotherapyClinical stage INational Cancer Data BaseEarly-stage esophageal cancerOverall survivalPositive surgical marginsPositive marginsUpfront esophagectomyEsophageal cancerStage IImproved survivalSurgical marginsMultivariable Cox regression analysisImproved overall survivalReceipt of chemotherapyCox regression analysisMultivariable logistic regressionEsophageal cancer patientsLog-rank testAdjuvant chemotherapyOS benefitPostoperative chemotherapyPN0 diseaseMultivariable analysisCancer patientsRole of Adjuvant Treatment in Esophageal Cancer With Incidental Pathologic Node Positivity
Gao SJ, Park HS, Corso CD, Rutter CE, Kim AW, Johung KL. Role of Adjuvant Treatment in Esophageal Cancer With Incidental Pathologic Node Positivity. The Annals Of Thoracic Surgery 2017, 104: 267-274. PMID: 28456393, DOI: 10.1016/j.athoracsur.2017.01.092.Peer-Reviewed Original ResearchConceptsMargin-positive patientsSurgical resectionEsophageal cancer patientsMargin-negative patientsAdjuvant treatmentChemoradiation therapyOverall survivalCarcinoma patientsCancer patientsMultivariable Cox regression analysisNational Cancer Data BaseSquamous cell carcinoma patientsPathologic nodal involvementPathologic node positivityConcurrent chemoradiation therapyAdjuvant chemoradiation therapyCell carcinoma patientsEsophageal carcinoma patientsCox regression analysisFurther prospective studiesOptimal adjuvant treatmentLog-rank testKaplan-Meier estimationAdjuvant chemotherapyN0 patients