Germline Copy Number Variation and Ovarian Cancer Survival
Fridley BL, Chalise P, Tsai YY, Sun Z, Vierkant RA, Larson MC, Cunningham JM, Iversen ES, Fenstermacher D, Barnholtz-Sloan J, Asmann Y, Risch HA, Schildkraut JM, Phelan CM, Sutphen R, Sellers TA, Goode EL. Germline Copy Number Variation and Ovarian Cancer Survival. Frontiers In Genetics 2012, 3: 142. PMID: 22891074, PMCID: PMC3413872, DOI: 10.3389/fgene.2012.00142.Peer-Reviewed Original ResearchSingle nucleotide polymorphismsGenome-wide arrayCopy number variationsCopy number changesSingle-marker approachGermline copy number variationsQuality control exclusionsChromosomal regionsNumber variationsNumber variantsNucleotide polymorphismsMultiple testing correctionCNV burdenConsecutive markersComplex diseasesLarge CNVsNumber changesChromosomal gainsSmall CNVsMarker approachCNVsGermline DNACNV probesCNV classificationComplementary approaches