2019
An experimental test of the ovulatory homolog model of female orgasm
Pavlicev M, Zupan AM, Barry A, Walters S, Milano KM, Kliman HJ, Wagner GP. An experimental test of the ovulatory homolog model of female orgasm. Proceedings Of The National Academy Of Sciences Of The United States Of America 2019, 116: 20267-20273. PMID: 31570579, PMCID: PMC6789565, DOI: 10.1073/pnas.1910295116.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBiological EvolutionChorionic GonadotropinCopulationFemaleFluoxetineMaleOvulationRabbitsReproductive Control AgentsSelective Serotonin Reuptake InhibitorsConceptsCopulation-induced ovulationOvulation rateEffects of fluoxetineHuman chorionic gonadotropinNeuro-endocrine mechanismsFluoxetine treatmentDaily dosesSerotonin functionChorionic gonadotropinSingle injectionPharmacological agentsFluoxetineFemale orgasmOvulationOrgasmRabbitsAnimalsGonadotropinDoses
1996
The effect of leukemia inhibitory factor (LIF) on trophoblast differentiation: a potential role in human implantation
Nachtigall MJ, Kliman HJ, Feinberg RF, Olive DL, Engin O, Arici A. The effect of leukemia inhibitory factor (LIF) on trophoblast differentiation: a potential role in human implantation. The Journal Of Clinical Endocrinology & Metabolism 1996, 81: 801-806. PMID: 8636307, DOI: 10.1210/jcem.81.2.8636307.Peer-Reviewed Original ResearchMeSH KeywordsBlotting, NorthernCell DifferentiationCells, CulturedChorionic GonadotropinChorionic Gonadotropin, beta Subunit, HumanEmbryo ImplantationFemaleFibronectinsGene ExpressionGrowth InhibitorsHumansInterleukin-6Leukemia Inhibitory FactorLymphokinesPregnancyProgesteroneRNA, MessengerTrophoblastsConceptsLeukemia inhibitory factorHuman cytotrophoblastsMenstrual cycle-dependent mannerInhibitory factorOncofetal fibronectinEffects of LIFHuman implantationHuman embryonic implantationBeta-HCG mRNAOncofetal fibronectin mRNAMessenger RNA expressionExtravillous phenotypeBeta-hCGMenstrual cycleHuman endometriumNormal implantationEmbryonic implantationProgesterone productionHCG mRNATerm placentaBiochemical markersCultured trophoblastsHuman CGDay 19Steroidogenic activity
1988
The human villous cytotrophoblast: Interactions with extracellular matrix proteins, endocrine function, and cytoplasmic differentiation in the absence of syncytium formation
Kao L, Caltabiano S, Wu S, Strauss J, Kliman H. The human villous cytotrophoblast: Interactions with extracellular matrix proteins, endocrine function, and cytoplasmic differentiation in the absence of syncytium formation. Developmental Biology 1988, 130: 693-702. PMID: 2848742, DOI: 10.1016/0012-1606(88)90361-2.Peer-Reviewed Original Research
1987
8-Bromo-Adenosine 3′,5′Monophosphate Regulates Expression of Chorionic Gonadotropin and Fibronectin in Human Cytotrophoblasts*
ULLOA-AGUIRRE A, AUGUST A, GOLOS T, KAO L, SAKURAGI N, KLIMAN H, STRAUSS J. 8-Bromo-Adenosine 3′,5′Monophosphate Regulates Expression of Chorionic Gonadotropin and Fibronectin in Human Cytotrophoblasts*. The Journal Of Clinical Endocrinology & Metabolism 1987, 64: 1002-1009. PMID: 2435752, DOI: 10.1210/jcem-64-5-1002.Peer-Reviewed Original Research8-Bromo Cyclic Adenosine MonophosphateChorionic GonadotropinChorionic Gonadotropin, beta Subunit, HumanCulture TechniquesFibronectinsGlycoprotein Hormones, alpha SubunitHumansImmunosorbent TechniquesMethionineMolecular WeightNucleic Acid HybridizationPeptide FragmentsPituitary Hormones, AnteriorRNA, MessengerTrophoblasts
1986
8-Bromo-3′5′ -Adenosine Monophosphate Stimulates the Endocrine Activity of Human Cytotrophoblasts in Culture*
FEINMAN M, KLIMAN H, CALTABIANO S, STRAUSS J. 8-Bromo-3′5′ -Adenosine Monophosphate Stimulates the Endocrine Activity of Human Cytotrophoblasts in Culture*. The Journal Of Clinical Endocrinology & Metabolism 1986, 63: 1211-1217. PMID: 3531221, DOI: 10.1210/jcem-63-5-1211.Peer-Reviewed Original ResearchGonadotropins and Cyclic Adenosine 3′,5′-Monophosphate (cAMP) Alter the Morphology of Cultured Human Granulosa Cells
Soto E, Kliman H, Strauss J, Paavola L. Gonadotropins and Cyclic Adenosine 3′,5′-Monophosphate (cAMP) Alter the Morphology of Cultured Human Granulosa Cells. Biology Of Reproduction 1986, 34: 559-569. PMID: 3008869, DOI: 10.1095/biolreprod34.3.559.Peer-Reviewed Original ResearchPurification, Characterization, and in vitro Differentiation of Cytotrophoblasts from Human Term Placentae*
KLIMAN H, NESTLER J, SERMASI E, SANGER J, STRAUSS J. Purification, Characterization, and in vitro Differentiation of Cytotrophoblasts from Human Term Placentae*. Endocrinology 1986, 118: 1567-1582. PMID: 3512258, DOI: 10.1210/endo-118-4-1567.Peer-Reviewed Original ResearchConceptsHuman term placentaTerm placentaImmunoperoxidase methodHCG-positive cellsOccasional single cellsPregnancy-specific beta 1Human placental lactogenPercoll gradient centrifugation stepDifferentiation of cytotrophoblastsPregnancy-specific betaFunctional syncytiotrophoblastsPlacental lactogenSyncytial groupsCultured trophoblastsHuman cytotrophoblastsOccasional cellsProgesterone synthesisSyncytial trophoblastHCGEndothelial cellsBeta 1CytotrophoblastsTrophoblastTime pointsPlacenta