2018
Type I interferons instigate fetal demise after Zika virus infection
Yockey LJ, Jurado KA, Arora N, Millet A, Rakib T, Milano KM, Hastings AK, Fikrig E, Kong Y, Horvath TL, Weatherbee S, Kliman HJ, Coyne CB, Iwasaki A. Type I interferons instigate fetal demise after Zika virus infection. Science Immunology 2018, 3 PMID: 29305462, PMCID: PMC6049088, DOI: 10.1126/sciimmunol.aao1680.Peer-Reviewed Original ResearchConceptsZika virus infectionZIKV infectionI IFNsI interferonType I interferonGrowth restrictionFetal demiseVirus infectionSevere fetal growth restrictionType I IFNsChorionic villous explantsAdverse fetal outcomesCongenital viral infectionFetal growth restrictionMaternal-fetal barrierType IFunctional type IPlacental damageFetal outcomesPregnancy complicationsEarly pregnancyFetal resorptionZIKV diseasePregnant damsSpontaneous abortion
2009
Determination of Placental Weight Using Two-dimensional Sonography and Volumetric Mathematic Modeling
Azpurua H, Funai E, Coraluzzi L, Doherty L, Sasson I, Kliman M, Kliman H. Determination of Placental Weight Using Two-dimensional Sonography and Volumetric Mathematic Modeling. American Journal Of Perinatology 2009, 27: 151-155. PMID: 19653142, DOI: 10.1055/s-0029-1234034.Peer-Reviewed Original ResearchMeSH KeywordsAdultFemaleFetal Growth RetardationHumansModels, BiologicalOrgan SizePlacentaPregnancyPregnancy Trimester, ThirdProspective StudiesReproducibility of ResultsUltrasonographyConceptsIntrauterine fetal demisePlacental weightPlacental volumePerinatal complicationsTwo-dimensional sonographyFetal growth restrictionThird trimester pregnancyHours of birthRoutine prenatal careHigh-risk casesSignificant correlationTwo-dimensional ultrasoundPlacental widthPreterm gestationFetal demisePrenatal careSubgroup analysisGrowth restrictionFetal movementsComplicationsSonographySpearman's rhoIUGRPregnancyGestation
2008
The fetus, not the mother, elicits maternal immunologic rejection: lessons from discordant dizygotic twin placentas
Yusuf K, Kliman HJ. The fetus, not the mother, elicits maternal immunologic rejection: lessons from discordant dizygotic twin placentas. Journal Of Perinatal Medicine 2008, 36: 291-296. PMID: 18598117, DOI: 10.1515/jpm.2008.054.Peer-Reviewed Original ResearchConceptsChronic villitisTwin placentasT cellsMaternal immunologic rejectionMaternal immune responseNumerous T cellsBirth weight differenceMouse monoclonal antibodyWeight discordancePathologic evidenceDizygotic pregnanciesAutoimmune disordersImmunologic rejectionDichorionic placentasHistologic examinationImmune responseVillitisBacterial infectionsPlacentaMonoclonal antibodiesChorionic villiFetusesMaternal environmentWeight differencesVilli
1994
Color Doppler flow patterns and flow velocity waveforms of the intraplacental fetal circulation in growth-retarded fetuses
Rotmensch S, Liberati M, Luo J, Kliman H, Gollin Y, Bellati U, Hobbins J, Copel J. Color Doppler flow patterns and flow velocity waveforms of the intraplacental fetal circulation in growth-retarded fetuses. American Journal Of Obstetrics And Gynecology 1994, 171: 1257-1264. PMID: 7977530, DOI: 10.1016/0002-9378(94)90143-0.Peer-Reviewed Original ResearchMeSH KeywordsBlood CirculationBlood Flow VelocityFemaleFetal Growth RetardationFetusHumansPlacentaPregnancyRegional Blood FlowUltrasonography, Doppler, ColorConceptsIntrauterine growth retardationFlow velocity waveformsUmbilical artery flow velocity waveformsColor Doppler flow signalsColor Doppler flow patternsDoppler flow signalsDoppler flow patternsVillous arteriesColor Doppler flowGrowth retardationVelocity waveformsFetal distressDoppler flowAbnormal umbilical artery flow velocity waveformsReversed end-diastolic flowDoppler flow velocity waveformsFlow signalsMedian Apgar scoresEnd-diastolic flowGrowth-retarded fetusesCross-sectional studyPulsed-wave DopplerApgar scoreColor Doppler flow imagesNormal pregnancy
1991
Preeclampsia, trisomy 13, and the placental bed.
Feinberg RF, Kliman HJ, Cohen AW. Preeclampsia, trisomy 13, and the placental bed. Obstetrics And Gynecology 1991, 78: 505-8. PMID: 1870809.Peer-Reviewed Original ResearchMeSH KeywordsAdultChromosomes, Human, Pair 13FemaleFetal DiseasesFetal Growth RetardationHumansPlacenta DiseasesPre-EclampsiaPregnancySyndromeTrisomyConceptsTrisomy 13Placental bedAbnormal trophoblastic invasionGrowth-retarded infantsNormal physiologic changesDevelopment of preeclampsiaMaternal uterine vasculatureFetal trisomy 13Severe preeclampsiaMultiparous womenSpiral arteriesUterine vasculatureTrophoblastic invasionPhysiologic changesTrophoblastic functionGenetic predispositionPreeclampsiaMultiparasBiopsyArteryPathophysiologyInfants