2012
Placental Protein 13 and Decidual Zones of Necrosis: An Immunologic Diversion That May be Linked to Preeclampsia
Kliman HJ, Sammar M, Grimpel YI, Lynch SK, Milano KM, Pick E, Bejar J, Arad A, Lee JJ, Meiri H, Gonen R. Placental Protein 13 and Decidual Zones of Necrosis: An Immunologic Diversion That May be Linked to Preeclampsia. Reproductive Sciences 2012, 19: 16-30. PMID: 21989657, DOI: 10.1177/1933719111424445.Peer-Reviewed Original ResearchConceptsPlacental protein 13Spiral arteriolesImmune cellsDecidual zoneProtein 13Decidual spiral arteriolesMaternal immune cellsWeeks of gestationElective pregnancy terminationHuman placental lactogenMaternal spiral arteriolesDecidual necrosisPregnancy terminationT cellsImmunohistochemical analysisDecidual veinsIntervillus spacePlacental lactogenInvasive trophoblastApoptosis markersPP13Chorionic villiNecrosisTrophoblastArterioles
2008
IFPA Meeting 2008 Workshops Report
Lash GE, Ansari T, Bischof P, Burton GJ, Chamley L, Crocker I, Dantzer V, Desoye G, Drewlo S, Fazleabas A, Jansson T, Keating S, Kliman HJ, Lang I, Mayhew T, Meiri H, Miller RK, Nelson DM, Pfarrer C, Roberts C, Sammar M, Sharma S, Shiverick K, Strunk D, Turner MA, Huppertz B. IFPA Meeting 2008 Workshops Report. Placenta 2008, 30: 4-14. PMID: 19084270, PMCID: PMC2668143, DOI: 10.1016/j.placenta.2008.11.014.Peer-Reviewed Original ResearchConceptsPlacental mesenchymal stem cellsIFPA annual meetingPlacental toxicologyPlacental pathologyPlacental transportTrophoblast subpopulationsMesenchymal stem cellsThemed workshopsStem cellsPlacentationFatty acidsInvasionWorkshop reportAnnual MeetingReportComparative placentationNeoplasiaPathologyTrophoblastImmunology
1992
Differentiation of the Trophoblast
Kliman H, Feinberg R. Differentiation of the Trophoblast. 1992, 3-25. DOI: 10.1007/978-3-642-84385-3_1.Peer-Reviewed Original ResearchOuter cell layersHuman trophoblastsTrophoblastic cell columnsDifferentiation pathwayUnique cellsDifferentiated functionsDifferentiation behaviorUndifferentiated cytotrophoblastsGestational ageIntermediate trophoblastSubsequent functionVillous syncytiotrophoblastCell columnVillous cytotrophoblastsHuman placentaTrophoblastCytotrophoblastsCell layerControl mechanismsBiologyDifferentiationPathwayBlastocystsPlacentaSyncytiotrophoblast
1990
Purified Human Cytotrophoblasts: Surrogates for The Blastocyst in In Vitro Models of Implantation?
Coutifaris C, Babalola G, Feinberg R, Kao L, Kliman H, Strauss J. Purified Human Cytotrophoblasts: Surrogates for The Blastocyst in In Vitro Models of Implantation? 1990, 687-695. DOI: 10.1007/978-1-4613-0645-0_74.Peer-Reviewed Original ResearchEndometrial epithelial cellsEpithelial cellsBasal laminaHuman embryo implantationEmbryo-maternal interactionsEndometrial stromaStromal invasionEpithelial destructionEmbryo implantationTrophoblastic cellsHuman cytotrophoblastsUterine epitheliumVitro modelImplantationNidationTrophoblastInterspecies differencesCells
1987
HLA antigen expression and induction by γ-interferon in cultured human trophoblasts
Feinman M, Kliman H, Main E. HLA antigen expression and induction by γ-interferon in cultured human trophoblasts. American Journal Of Obstetrics And Gynecology 1987, 157: 1429-1434. PMID: 3122576, DOI: 10.1016/s0002-9378(87)80238-7.Peer-Reviewed Original ResearchConceptsHuman trophoblastsHLA antigen expressionHLA class I heavy chainsClass II antigensClass I HLACultured human trophoblastsHLA heavy chainsPregnancy complicationsHLA antigensClass I heavy chainsII antigensAntigen expressionHeavy chainI HLAΓ-interferonImmunocytochemical studyAntigenMonoclonal antibodiesClass ICellular stainingTime courseTrophoblastCytotrophoblastsExpressionGene expressionDifferentiaton of Human Cytotrophoblast into Syncytiotrophoblast in Culture
Kliman H, Feinman M, Strauss J. Differentiaton of Human Cytotrophoblast into Syncytiotrophoblast in Culture. Trophoblast Research 1987, 407-421. DOI: 10.1007/978-1-4757-1936-9_29.Peer-Reviewed Original ResearchHuman chorionic gonadotropinHuman placental lactogenPrevention of rejectionPatterns of hCGHuman term placentaFetal circulationMononuclear cellsProgesterone secretionChorionic gonadotropinPlacental lactogenTerm placentaHuman cytotrophoblastsImmunoglobulin transportTrophoblastImmunocytochemical localizationProtein hormonesSyncytiotrophoblastCytotrophoblastsFetusesMothersEarlier reportsMorphological changesReportSyncytial structureCells
1986
Purification, Characterization, and in vitro Differentiation of Cytotrophoblasts from Human Term Placentae*
KLIMAN H, NESTLER J, SERMASI E, SANGER J, STRAUSS J. Purification, Characterization, and in vitro Differentiation of Cytotrophoblasts from Human Term Placentae*. Endocrinology 1986, 118: 1567-1582. PMID: 3512258, DOI: 10.1210/endo-118-4-1567.Peer-Reviewed Original ResearchConceptsHuman term placentaTerm placentaImmunoperoxidase methodHCG-positive cellsOccasional single cellsPregnancy-specific beta 1Human placental lactogenPercoll gradient centrifugation stepDifferentiation of cytotrophoblastsPregnancy-specific betaFunctional syncytiotrophoblastsPlacental lactogenSyncytial groupsCultured trophoblastsHuman cytotrophoblastsOccasional cellsProgesterone synthesisSyncytial trophoblastHCGEndothelial cellsBeta 1CytotrophoblastsTrophoblastTime pointsPlacenta