Efficacy of telotristat ethyl: A peripheral tryptophan hydroxylase inhibitor that blocks serotonin biosynthesis against cultured liposarcoma, colon cancer, and cholangiocarcinoma cell lines.
Kliman H, Ling I, Milano K. Efficacy of telotristat ethyl: A peripheral tryptophan hydroxylase inhibitor that blocks serotonin biosynthesis against cultured liposarcoma, colon cancer, and cholangiocarcinoma cell lines. Journal Of Clinical Oncology 2020, 38: e15602-e15602. DOI: 10.1200/jco.2020.38.15_suppl.e15602.Peer-Reviewed Original ResearchTelotristat ethylTryptophan hydroxylase inhibitorCholangiocarcinoma cell linesCancer cell linesHydroxylase inhibitorColon cancerCell linesTE groupPR-positive breast cancerPositive breast cancerBlood-brain barrierCentral nervous systemLiposarcoma cell lineColon cancer cell linesLow power microscopic examinationPeripheral cancersCell line growthPositive cancersBrain barrierHT-29 cellsBreast cancerTPH inhibitorsCell confluenceNervous systemTumor cell line growth