Preeclampsia, trisomy 13, and the placental bed.
Feinberg RF, Kliman HJ, Cohen AW. Preeclampsia, trisomy 13, and the placental bed. Obstetrics And Gynecology 1991, 78: 505-8. PMID: 1870809.Peer-Reviewed Original ResearchConceptsTrisomy 13Placental bedAbnormal trophoblastic invasionGrowth-retarded infantsNormal physiologic changesDevelopment of preeclampsiaMaternal uterine vasculatureFetal trisomy 13Severe preeclampsiaMultiparous womenSpiral arteriesUterine vasculatureTrophoblastic invasionPhysiologic changesTrophoblastic functionGenetic predispositionPreeclampsiaMultiparasBiopsyArteryPathophysiologyInfantsFetal akinesia deformation sequence (Pena-Shokeir phenotype) associated with acquired intrauterine brain damage.
Lavi E, Montone K, Rorke L, Kliman H. Fetal akinesia deformation sequence (Pena-Shokeir phenotype) associated with acquired intrauterine brain damage. Neurology 1991, 41: 1467-8. PMID: 1891100, DOI: 10.1212/wnl.41.9.1467.Peer-Reviewed Original ResearchConceptsIntrauterine brain damageFocal cerebral infarctionTetralogy of FallotFetal akinesia deformation sequenceCocaine-using mothersPena-Shokeir phenotypeDiffuse brainstemCerebral infarctionNeuropathologic findingsPulmonary hypoplasiaIschemic damagePathologic findingsNeuronal degenerationBrain damageFacial anomaliesFallotInfarctionBrainstemTetralogyInfantsHypoplasiaCamptodactylyArthrogryposisFindingsDegeneration