2022
Trophoblast inclusions and adverse birth outcomes
Firestein MR, Kliman HJ, Sania A, Brink LT, Holzer PH, Hofmann KM, Milano KM, Pini N, Shuffrey LC, Odendaal HJ, Fifer WP. Trophoblast inclusions and adverse birth outcomes. PLOS ONE 2022, 17: e0264733. PMID: 35231069, PMCID: PMC8887719, DOI: 10.1371/journal.pone.0264733.Peer-Reviewed Original ResearchConceptsBirth outcomesGestational ageLiveborn deliveryLive birthsFull-term live birthsChorionic villiPreterm live birthsSpecific placental pathologyFull-term birthInduction of laborAdverse birth outcomesGestational age birthweightSafe Passage StudyTrophoblast inclusionsGreater odds ratioWarrants further investigationPlacental infarctionPlacenta accretaPreterm birthPlacental pathologyVillous edemaPatient populationAlcohol exposureOdds ratioChorionic plate
2017
Estimated Placental Volume and Gestational Age
Isakov KMM, Emerson JW, Campbell KH, Galerneau F, Anders AM, Lee YK, Subramanyam P, Roberts AE, Kliman HJ. Estimated Placental Volume and Gestational Age. American Journal Of Perinatology 2017, 35: 748-757. PMID: 29281842, DOI: 10.1055/s-0037-1615285.Peer-Reviewed Original ResearchConceptsGestational ageBirth weightPlacental volumeSignificant placental pathologyWeeks gestational agePlacental pathologyUltrasound scanClinical utilityNormative curvesMicroscopic evaluationPatientsFurther validationVariety of settingsAgePercentileEPVDifferent populationsSubanalysisGestationNewbornsPlacentaPathology
2013
Utilizing Two-Dimensional Ultrasound to Develop Normative Curves for Estimated Placental Volume
Arleo EK, Troiano RN, da Silva R, Greenbaum D, Kliman HJ. Utilizing Two-Dimensional Ultrasound to Develop Normative Curves for Estimated Placental Volume. American Journal Of Perinatology 2013, 31: 683-688. PMID: 24108663, DOI: 10.1055/s-0033-1357265.Peer-Reviewed Original Research
2007
Reference Weights for Placentas Delivered before the 28th Week of Gestation
Hecht JL, Kliman HJ, Allred EN, Pflueger SM, Chang C, Doss BJ, Roberts D, Livasy CA, Bhan I, Zambrano E, Ross DW, Senagore P, Husain AN, Leviton A. Reference Weights for Placentas Delivered before the 28th Week of Gestation. Placenta 2007, 28: 987-990. PMID: 17573110, DOI: 10.1016/j.placenta.2007.04.009.Peer-Reviewed Original ResearchConceptsPost-menstrual weeksSingleton placentasBirth weightPlacenta weightBirth weight z-scoreStandard weight tableWeight z-scoreSmall birth weightWeeks of gestationFetal indicationsLive infantsGestational ageTwin placentasPoor perfusionGrowth restrictionLarger sample sizeZ-scorePlacentaWeeksFetal processesStandard weightReference weightSample sizePreeclampsiaPregnancy
1992
Differentiation of the Trophoblast
Kliman H, Feinberg R. Differentiation of the Trophoblast. 1992, 3-25. DOI: 10.1007/978-3-642-84385-3_1.Peer-Reviewed Original ResearchOuter cell layersHuman trophoblastsTrophoblastic cell columnsDifferentiation pathwayUnique cellsDifferentiated functionsDifferentiation behaviorUndifferentiated cytotrophoblastsGestational ageIntermediate trophoblastSubsequent functionVillous syncytiotrophoblastCell columnVillous cytotrophoblastsHuman placentaTrophoblastCytotrophoblastsCell layerControl mechanismsBiologyDifferentiationPathwayBlastocystsPlacentaSyncytiotrophoblast