2017
Luteal start vaginal micronized progesterone improves pregnancy success in women with recurrent pregnancy loss
Stephenson MD, McQueen D, Winter M, Kliman HJ. Luteal start vaginal micronized progesterone improves pregnancy success in women with recurrent pregnancy loss. Fertility And Sterility 2017, 107: 684-690.e2. PMID: 28081870, DOI: 10.1016/j.fertnstert.2016.11.029.Peer-Reviewed Original ResearchConceptsPregnancy successEndometrial biopsySubsequent pregnancyLH surgePregnancy lossVaginal micronized progesteroneObservational cohort studyUnexplained pregnancy lossRecurrent pregnancy lossCohort of womenCyclin E expressionMicronized progesteronePrior pregnancyCohort studyOngoing pregnancyConcomitant findingsEndometrial glandsOdds ratioInclusion criteriaMAIN OUTCOMEPregnancyE expressionWomenCohortWeeks
2006
Optimization of endometrial preparation results in a normal endometrial function test® (EFT®) and good reproductive outcome in donor ovum recipients
Kliman HJ, Honig S, Walls D, Luna M, McSweet JC, Copperman AB. Optimization of endometrial preparation results in a normal endometrial function test® (EFT®) and good reproductive outcome in donor ovum recipients. Journal Of Assisted Reproduction And Genetics 2006, 23: 299-303. PMID: 16983518, DOI: 10.1007/s10815-006-9061-1.Peer-Reviewed Original ResearchConceptsFunction testsCourse of estrogensOvum donation cyclesUnexplained infertility patientsBetter reproductive outcomesCyclin EOvum recipientsClinical pregnancyEndometrial biopsyInfertility patientsProgesterone supplementationSuch patientsEndometrial receptivityDonation cyclesSuccessful pregnancyPregnancy failureDonor oocytesLeuprolide acetateSole patientUterine preparationsImmunohistochemical stainingReproductive outcomesStimulation protocolTransfer cyclesSuccessful implantationMouse ascites Golgi mucin expression abnormalities in natural cycle endometrial biopsies predict subsequent in vitro fertilization–embryo transfer (IVF-ET) failure in patients with previous IVF-ET failures
Catalanotti JS, Spandorfer SD, Barmat LI, Rosenwaks Z, McSweet JC, Kliman HJ. Mouse ascites Golgi mucin expression abnormalities in natural cycle endometrial biopsies predict subsequent in vitro fertilization–embryo transfer (IVF-ET) failure in patients with previous IVF-ET failures. Fertility And Sterility 2006, 85: 255-258. PMID: 16412771, DOI: 10.1016/j.fertnstert.2005.06.060.Peer-Reviewed Original ResearchConceptsIVF-ET failureFertilization-embryo transfer failureIVF-ET outcomeClinical pregnancy rateRetrospective cohort studyHigh positive predictive valuePositive predictive valueCohort studyEndometrial biopsyIVF-ETEndometrial expressionPregnancy ratePredictive valueExpression abnormalitiesAbnormal miceSignificant decreaseMiceWomenTransfer failureFailureBiopsyPatientsExpressionAbnormalitiesGolgi expression
2003
Improved endometrial assessment using cyclin E and p27
Dubowy RL, Feinberg RF, Keefe DL, Doncel GF, Williams SC, McSweet JC, Kliman HJ. Improved endometrial assessment using cyclin E and p27. Fertility And Sterility 2003, 80: 146-156. PMID: 12849817, DOI: 10.1016/s0015-0282(03)00573-9.Peer-Reviewed Original ResearchConceptsCyclin EDay 20Retrospective clinical studyNormal control biopsiesUniversity Medical CenterEndometrial assessmentMock cycleP27 immunohistochemistryEndometrial biopsyControl biopsiesInfertile womenInfertility patientsEndometrial expressionMenstrual cycleInfertility treatmentClinical studiesMedical CenterMAIN OUTCOMEP27 stainingFertile volunteersP27 expressionDay 17Useful markerProliferative samplesBiopsy
2000
Endometrial dating and determination of the window of implantation in healthy fertile women
Acosta A, Elberger L, Borghi M, Calamera J, Chemes H, Doncel G, Kliman H, Lema B, Lustig L, Papier S. Endometrial dating and determination of the window of implantation in healthy fertile women. Fertility And Sterility 2000, 73: 788-798. PMID: 10731542, DOI: 10.1016/s0015-0282(99)00605-6.Peer-Reviewed Original ResearchMeSH KeywordsAdultEmbryo ImplantationEndometriumEstradiolFemaleFollicle Stimulating HormoneGolgi ApparatusGrowth InhibitorsHumansImmunohistochemistryIntegrin alpha4beta1IntegrinsInterleukin-6Leukemia Inhibitory FactorLuteinizing HormoneLymphokinesMenstrual CycleMicroscopy, Electron, ScanningMucinsProspective StudiesReceptors, Interleukin-1Receptors, Interleukin-1 Type IReceptors, Lymphocyte HomingReceptors, ProgesteroneReceptors, VitronectinReference ValuesConceptsWindow of implantationLeukemia inhibitory factorLuteal phaseDay 22Day 20Endometrial datingInterleukin-1 receptor type IAssisted reproductive unitWhole luteal phaseProspective clinical studyHealthy fertile womenIL-1R tIReceptor type IMAG antibodyEndometrial biopsyFertile womenNormal womenImplantation windowP4 receptorReceptor expressionClinical studiesLH peakHealthy volunteersMAIN OUTCOMEImmunohistochemical determination
1995
A mucin-like glycoprotein identified by MAG (mouse ascites Golgi) antibodies. Menstrual cycle-dependent localization in human endometrium.
Kliman HJ, Feinberg RF, Schwartz LB, Feinman MA, Lavi E, Meaddough EL. A mucin-like glycoprotein identified by MAG (mouse ascites Golgi) antibodies. Menstrual cycle-dependent localization in human endometrium. American Journal Of Pathology 1995, 146: 166-81. PMID: 7531946, PMCID: PMC1870765.Peer-Reviewed Original ResearchConceptsMAG antibodyMucin-like glycoproteinHigh molecular weight mucin-like glycoproteinBlood groupCycle days 5Bile duct epitheliumAnti-MAG antibodiesConceptus-endometrial interactionsExpression of mucinsBlood type ABlood group AHuman endometrial glandsEndometrial biopsyPancreatic acinar cellsEndometrial glandsEndometrial surfaceIgG antibodiesImplantation windowHuman endometriumImmunohistochemical stainingGroup AGall bladderLuminal epitheliumDuct epitheliumLacrimal gland