1987
Thresholds for physiological effects of plasma catecholamines in fetal sheep
Padbury J, Ludlow J, Ervin M, Jacobs H, Humme J. Thresholds for physiological effects of plasma catecholamines in fetal sheep. American Journal Of Physiology 1987, 252: e530-e537. PMID: 3565562, DOI: 10.1152/ajpendo.1987.252.4.e530.Peer-Reviewed Original ResearchConceptsBlood pressurePlasma concentrationsFetal sheepPg/Plasma free fatty acidsDiastolic blood pressureSystolic blood pressurePlasma catecholamine levelsFull-term animalsInfusion of norepinephrineMinimum plasma concentrationDose-response curvePlasma catecholamine valuesInfused norepinephrineHigher peak responsesNeonatal adaptationCatecholamine levelsPlasma catecholaminesPreterm animalsFree fatty acidsGlucose levelsE concentrationsCatecholamine valuesNorepinephrineMarked increase
1986
Hemodynamic Effects of High Frequency Ventilation in Surfactant-Treated Preterm Lambs
Oguchi K, Baylen B, Ikegami M, Jacobs H, Berry D, Jobe A, Emmanouilides G. Hemodynamic Effects of High Frequency Ventilation in Surfactant-Treated Preterm Lambs. Neonatology 1986, 49: 21-28. PMID: 3753885, DOI: 10.1159/000242505.Peer-Reviewed Original ResearchConceptsHigh-frequency ventilationConventional ventilationHemodynamic effectsDuctus arteriosusPreterm lambsFrequency ventilationSame mean airway pressureLV end-diastolic volumeRight ductal shuntSurfactant-treated lambsMean airway pressureDeleterious hemodynamic effectsOrgan blood flowMin of ageEnd-diastolic volumeBlood gas valuesDays gestational ageLV stroke volumeBlood flow measurementsComparable ventilationDuctal shuntAirway pressureDuctal occlusionHemodynamic statusArterial pressure