1997
Repeated Doses of the Perfluorocarbon FC-100 Improve Lung Function of Preterm Lambs
Moya F, Llanos A, Ríos A, Riquelme R, Moraga F, Rubio L, Salvo H, Jacobs H. Repeated Doses of the Perfluorocarbon FC-100 Improve Lung Function of Preterm Lambs. Pediatric Research 1997, 42: 893-898. PMID: 9396575, DOI: 10.1203/00006450-199712000-00028.Peer-Reviewed Original ResearchConceptsLung functionPreterm lambsInitial doseIntratracheal administrationFC-100Administration of ExosurfSurfactant-deficient animalsSynthetic surfactant ExosurfArterial blood pressureDynamic lung compliancePreterm neonatesBlood pressureLung complianceSingle doseArterial PO2Arterial PCO2Surfactant deficiencyHeart rateAdditional doseExosurfStudy periodDoseAdministrationDosesSimilar changes
1985
Normalization of Arterial Blood Gases after Treatment of Surfactant-Deficient Lambs with Tween 201–3
Jacobs H, Berry D, Duane G, Ikegami M, Jobe A, Jones S. Normalization of Arterial Blood Gases after Treatment of Surfactant-Deficient Lambs with Tween 201–3. American Journal Of Respiratory And Critical Care Medicine 1985, 132: 1313-8. PMID: 3935021, DOI: 10.1164/arrd.1985.132.6.1313.Peer-Reviewed Original ResearchConceptsPeak inspiratory pressurePulmonary surfactantAdequate ventilationMinimal surface tensionArterial blood gasesNormal lung functionMin of ageRespiratory failureLung functionLung complianceInspiratory pressureBlood gasesInfant ventilatorDays gestationAlveolar washControl animalsControl lambsPoor oxygenationSurfactant treatmentGas exchangeTreatmentVentilationLambsGestationVentilator