2017
Prehospital Delay in Older Adults with Acute Myocardial Infarction: The ComprehenSIVe Evaluation of Risk Factors in Older Patients with Acute Myocardial Infarction Study
Ouellet GM, Geda M, Murphy TE, Tsang S, Tinetti ME, Chaudhry SI. Prehospital Delay in Older Adults with Acute Myocardial Infarction: The ComprehenSIVe Evaluation of Risk Factors in Older Patients with Acute Myocardial Infarction Study. Journal Of The American Geriatrics Society 2017, 65: 2391-2396. PMID: 29044463, PMCID: PMC5681402, DOI: 10.1111/jgs.15102.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionAcute Myocardial Infarction StudyMyocardial Infarction StudyPrehospital delayOlder adultsOlder patientsHeart failureMyocardial infarctionRisk factorsFuture public health effortsContemporary national cohortMedical record abstractionPublic health effortsCross-sectional analysisAntiischemic therapyHospital presentationIndex hospitalizationHospital delaySymptom durationDiabetes mellitusClinical presentationComorbid conditionsRecord abstractionAtypical symptomsNonwhite race
2012
Combined assessment of sex- and mutation-specific information for risk stratification in type 1 long QT syndrome
Costa J, Lopes CM, Barsheshet A, Moss AJ, Migdalovich D, Ouellet G, McNitt S, Polonsky S, Robinson JL, Zareba W, Ackerman MJ, Benhorin J, Kaufman ES, Platonov PG, Shimizu W, Towbin JA, Vincent GM, Wilde AA, Goldenberg I. Combined assessment of sex- and mutation-specific information for risk stratification in type 1 long QT syndrome. Heart Rhythm 2012, 9: 892-898. PMID: 22293141, PMCID: PMC3358462, DOI: 10.1016/j.hrthm.2012.01.020.Peer-Reviewed Original ResearchConceptsCardiac eventsLife-threatening cardiac eventsSex-specific risk factorsSex-specific riskAge 40 yearsLife-threatening eventsType 1 long QT syndromeLong QT syndromeRisk stratificationRisk factorsQT intervalHigh riskTime-dependent differencesQT syndromeMultivariate analysisLQT1WomenCombined assessmentKCNQ1 geneDisease-causing mutationsMenRiskOnset of adolescenceMutation-specific informationSCD
2011
Mutation and gender-specific risk in type 2 long QT syndrome: Implications for risk stratification for life-threatening cardiac events in patients with long QT syndrome
Migdalovich D, Moss AJ, Lopes CM, Costa J, Ouellet G, Barsheshet A, McNitt S, Polonsky S, Robinson JL, Zareba W, Ackerman MJ, Benhorin J, Kaufman ES, Platonov PG, Shimizu W, Towbin JA, Vincent GM, Wilde AA, Goldenberg I. Mutation and gender-specific risk in type 2 long QT syndrome: Implications for risk stratification for life-threatening cardiac events in patients with long QT syndrome. Heart Rhythm 2011, 8: 1537-1543. PMID: 21440677, PMCID: PMC4028036, DOI: 10.1016/j.hrthm.2011.03.049.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultChildChild, PreschoolChi-Square DistributionDeath, Sudden, CardiacERG1 Potassium ChannelEther-A-Go-Go Potassium ChannelsFemaleHeart ArrestHumansInfantInfant, NewbornLong QT SyndromeMaleMutationProbabilityProportional Hazards ModelsRegistriesRisk AssessmentSex FactorsStatistics, NonparametricSurvival AnalysisConceptsLife-threatening cardiac eventsCardiac eventsLong QT syndromeGender-specific riskRisk stratificationQT syndromeKCNH2 channelsImproved risk stratificationType 2 long QT syndromeAge 40 yearsLife-threatening eventsLQT2 womenFemale patientsHigh riskLQT2 patientsTime-dependent differencesMultivariate analysisPatientsCombined assessmentCumulative probabilityWomenDisease-causing mutationsLoop mutationsMenRisk