Influence of Diabetes Mellitus on Outcome in Patients Over 40 Years of Age With the Long QT Syndrome
Ouellet G, Moss AJ, Jons C, McNitt S, Mullally J, Fugate T, Goldenberg I, Zareba W, Robinson JL, Registry I. Influence of Diabetes Mellitus on Outcome in Patients Over 40 Years of Age With the Long QT Syndrome. The American Journal Of Cardiology 2009, 105: 87-89. PMID: 20102896, PMCID: PMC2813216, DOI: 10.1016/j.amjcard.2009.08.657.Peer-Reviewed Original ResearchConceptsYears of ageFirst cardiac eventLong QT syndromeCardiac eventsQTc intervalRisk factorsAdult patientsDiabetes mellitusQT syndromeEnd pointIndependent mortality riskOral diabetic medicationsProlonged QTc intervalImpact of diabetesDevelopment of diabetesBeats/minInternational Long QT Syndrome RegistryCause mortalityDiabetic medicationsOlder patientsStudy populationVentricular repolarizationMortality riskHeart rateCox modelClinical Implications for Patients With Long QT Syndrome Who Experience a Cardiac Event During Infancy
Spazzolini C, Mullally J, Moss AJ, Schwartz PJ, McNitt S, Ouellet G, Fugate T, Goldenberg I, Jons C, Zareba W, Robinson JL, Ackerman MJ, Benhorin J, Crotti L, Kaufman ES, Locati EH, Qi M, Napolitano C, Priori SG, Towbin JA, Vincent GM. Clinical Implications for Patients With Long QT Syndrome Who Experience a Cardiac Event During Infancy. Journal Of The American College Of Cardiology 2009, 54: 832-837. PMID: 19695463, PMCID: PMC3517782, DOI: 10.1016/j.jacc.2009.05.029.Peer-Reviewed Original ResearchConceptsSudden cardiac deathLong QT syndromeCardiac eventsQT syndromeHeart rateClinical implicationsFirst yearBeta-blocker therapyHigh-risk subsetInternational LQTS RegistryBeats/minAge 1 yearYears of lifeHazard ratioCardiac deathSyncopal episodesCardiac arrestLQTS RegistryFemale sexPrognostic aspectsQT intervalStudy populationHigh riskPatientsSyndrome