2014
Multivariate analysis reveals genetic associations of the resting default mode network in psychotic bipolar disorder and schizophrenia
Meda SA, Ruaño G, Windemuth A, O’Neil K, Berwise C, Dunn SM, Boccaccio LE, Narayanan B, Kocherla M, Sprooten E, Keshavan MS, Tamminga CA, Sweeney JA, Clementz BA, Calhoun VD, Pearlson GD. Multivariate analysis reveals genetic associations of the resting default mode network in psychotic bipolar disorder and schizophrenia. Proceedings Of The National Academy Of Sciences Of The United States Of America 2014, 111: e2066-e2075. PMID: 24778245, PMCID: PMC4024891, DOI: 10.1073/pnas.1313093111.Peer-Reviewed Original ResearchConceptsDefault mode networkPsychotic bipolar disorderUnaffected first-degree relativesFirst-degree relativesSZ probandsResting-state functional MRI scansBipolar disorderMode networkFunctional MRI scansLong-term potentiationBrain's default mode networkGlobal enrichment analysisSubset of controlsPatient groupHealthy controlsDMN modulationDrug treatmentImmune responsePsychiatric disordersStudy subjectsMRI scansDMN connectivityMultivariate analysisFunctional connectivitySchizophrenia
2012
Three-way FMRI-DTI-methylation data fusion based on mCCA+jICA and its application to schizophrenia
Sui J, He H, Liu J, Yu Q, Adali T, Pearlson G, Calhoun V. Three-way FMRI-DTI-methylation data fusion based on mCCA+jICA and its application to schizophrenia. Annual International Conference Of The IEEE Engineering In Medicine And Biology Society (EMBC) 2012, 2012: 2692-2695. PMID: 23366480, DOI: 10.1109/embc.2012.6346519.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlgorithmsFemaleHumansMagnetic Resonance ImagingMaleMultivariate AnalysisSchizophreniaYoung AdultConceptsMulti-set canonical correlation analysisData fusionMulti-modal fusionDisparate data setsMultiple data typesJoint independent component analysisData typesFusion modelJoint informationData setsIndependent component analysisHigher decomposition accuracyEffective mannerCanonical correlation analysisDecomposition accuracyLimited viewEffective approachPromising approachBiomedical imagingFusionComponent analysisAccuracyIllness biomarkersInformationSet
1996
Eye Movements and Psychopathology in Schizophrenia and Bipolar Disorder
TIEN A, ROSS D, PEARLSON G, STRAUSS M. Eye Movements and Psychopathology in Schizophrenia and Bipolar Disorder. The Journal Of Nervous And Mental Disease 1996, 184: 331-338. PMID: 8642381, DOI: 10.1097/00005053-199606000-00001.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsAgedAttentionBipolar DisorderEye MovementsFemaleHumansIntelligence TestsMaleMiddle AgedMultivariate AnalysisNeuropsychological TestsPsychiatric Status Rating ScalesPursuit, SmoothReaction TimeRegression AnalysisSaccadesSchizophreniaSchizophrenic PsychologySex FactorsVisual Perception