2022
What can clozapine’s effect on neural oscillations tell us about its therapeutic effects? A scoping review and synthesis
Raymond N, Lizano P, Kelly S, Hegde R, Keedy S, Pearlson G, Gershon E, Clementz B, Tamminga C, Keshavan M. What can clozapine’s effect on neural oscillations tell us about its therapeutic effects? A scoping review and synthesis. Biomarkers In Neuropsychiatry 2022, 6: 100048. DOI: 10.1016/j.bionps.2022.100048.Peer-Reviewed Original ResearchTherapeutic effectNeural oscillationsTreatment-resistant schizophreniaEffects of clozapineElectrical activityRate of seizuresResistant schizophreniaBrain electrical activityClozapinePotential mechanismsSlow wavesSynthesis of findingsSchizophreniaLiterature pertainingHypothesis-driven investigationsReviewElectroencephalogramSeizuresFindingsIndividualsBiomarkers
2020
Functional MRI Findings in Schizophrenia
Pearlson G. Functional MRI Findings in Schizophrenia. 2020, 113-124. DOI: 10.1007/978-3-030-35206-6_6.Peer-Reviewed Original ResearchSchizophrenia patientsDrug-naïve patientsFunctional MRI findingsFunctional MRI literatureTask-related paradigmsMRI findingsMedication treatmentPredisposing causeHealthy controlsFunctional abnormalitiesMRI reportsPsychotic bipolarNeurodevelopmental anomaliesPatientsBrain differencesUnaffected relativesSynaptic efficiencySchizophreniaMRI literatureAbnormalitiesArticle reviewsLocal manifestationsReviewSymptomsNeurotransmitters
1999
Structural brain imaging in schizophrenia: a selective review
Pearlson G, Marsh L. Structural brain imaging in schizophrenia: a selective review. Biological Psychiatry 1999, 46: 627-649. PMID: 10472416, DOI: 10.1016/s0006-3223(99)00071-2.Peer-Reviewed Original ResearchConceptsStructural neuroimaging studiesRegional brain volume abnormalitiesBrain structuresNeuroimaging studiesLateral ventricular enlargementPathophysiology of schizophreniaAbnormal brain structureBrain volume abnormalitiesComputed tomography studyNeuroanatomic pathologyVentricular enlargementBrain abnormalitiesAnatomic findingsVolume abnormalitiesStructural brainSchizophreniaTomography studySelective reviewAbnormalitiesConsistent evidenceBrainGenetic influencesReviewPathophysiologyFindingsStructural and functional brain changes in bipolar disorder: a selective review
Pearlson G. Structural and functional brain changes in bipolar disorder: a selective review. Schizophrenia Research 1999, 39: 133-140. PMID: 10507524, DOI: 10.1016/s0920-9964(99)00112-7.Peer-Reviewed Original Research