2016
Isoforms of Spectrin and Ankyrin Reflect the Functional Topography of the Mouse Kidney
Stankewich MC, Moeckel GW, Ji L, Ardito T, Morrow JS. Isoforms of Spectrin and Ankyrin Reflect the Functional Topography of the Mouse Kidney. PLOS ONE 2016, 11: e0142687. PMID: 26727517, PMCID: PMC4703142, DOI: 10.1371/journal.pone.0142687.Peer-Reviewed Original ResearchConceptsBowman's capsuleEndothelial cellsFunctional topographyThick ascending loopGlomerular endothelial cellsProximal tubule cellsCapillary endothelial cellsAscending loopDistal tubulesDistal nephronTubule cellsTubular segmentsKidneyRodent kidneyWestern blottingMouse kidneyImmuno-electron microscopyThick loopAnkyrin GMetabolite traffickingSpectrin scaffoldHenleNephronCapsulePodocytes
2008
Apoptosis of the Thick Ascending Limb Results in Acute Kidney Injury
Srichai MB, Hao C, Davis L, Golovin A, Zhao M, Moeckel G, Dunn S, Bulus N, Harris RC, Zent R, Breyer MD. Apoptosis of the Thick Ascending Limb Results in Acute Kidney Injury. Journal Of The American Society Of Nephrology 2008, 19: 1538-1546. PMID: 18495962, PMCID: PMC2488270, DOI: 10.1681/asn.2007101101.Peer-Reviewed Original ResearchConceptsAcute kidney injuryKidney injuryToxin-induced acute kidney injurySevere acute kidney injuryNovel transgenic mouse modelAdministration of gancyclovirIschemia/reperfusionBlood urea nitrogenTransgenic mouse modelToxin-induced injuryThick ascending limbHerpes simplex virus 1 thymidine kinase geneCreatinine levelsNeutrophil infiltrationAcute injuryControl miceInjury resultsMouse modelTransgenic miceUrea nitrogenProximal tubulesTAL cellsAscending limbInjuryTubular segments