2011
Rapid Diagnosis of Tuberculosis and Multidrug Resistance by the Microscopic-Observation Drug-Susceptibility Assay
Shah NS, Moodley P, Babaria P, Moodley S, Ramtahal M, Richardson J, Heysell S, Li X, Moll A, Friedland G, Sturm AW, Gandhi NR. Rapid Diagnosis of Tuberculosis and Multidrug Resistance by the Microscopic-Observation Drug-Susceptibility Assay. American Journal Of Respiratory And Critical Care Medicine 2011, 183: 1427-1433. PMID: 21297071, DOI: 10.1164/rccm.201009-1449oc.Peer-Reviewed Original ResearchConceptsDrug susceptibility testingMDR-TB diagnosisMDR-TBHIV statusMultidrug-resistant (MDR) TBProportion methodRapid diagnosisProspective diagnostic accuracy studyAdult TB suspectsMicroscopic-Observation DrugReference standard cultureMedian CD4 countPatient's HIV statusHIV prevalence settingsIndirect proportion methodMycobacterial growth indicator tube (MGIT) cultureMedian turnaround timeResource-limited settingsReference standardDiagnostic accuracy studiesCD4 countMycobacterium tuberculosis detectionConsecutive adultsTB suspectsHIV prevalence
2009
Treatment outcomes among patients with multidrug-resistant tuberculosis: systematic review and meta-analysis
Orenstein EW, Basu S, Shah NS, Andrews JR, Friedland GH, Moll AP, Gandhi NR, Galvani AP. Treatment outcomes among patients with multidrug-resistant tuberculosis: systematic review and meta-analysis. The Lancet Infectious Diseases 2009, 9: 153-161. PMID: 19246019, DOI: 10.1016/s1473-3099(09)70041-6.Peer-Reviewed Original ResearchConceptsMultidrug-resistant tuberculosisTreatment outcomesHIV statusTreatment regimensStrong patient supportProportion of patientsPatient's HIV statusTuberculosis treatment programmesHigher treatment successSuccessful treatment outcomePublic health concernStandardised regimensMDR tuberculosisObserved therapyPatient populationTreatment completionTreatment successInclusion criteriaPatient supportTherapeutic studiesClinical reportsTreatment approachesTreatment durationPatientsSystematic review
2000
Antiretroviral Prophylaxis of Health Care Workers at Two Urban Medical Centers
Russi M, Buitrago M, Goulet J, Calello D, Perlotto J, van Rhijn D, Nash E, Friedland G, Hierholzer W. Antiretroviral Prophylaxis of Health Care Workers at Two Urban Medical Centers. Journal Of Occupational And Environmental Medicine 2000, 42: 1092-1100. PMID: 11094788, DOI: 10.1097/00043764-200011000-00011.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnti-HIV AgentsBlood-Borne PathogensChi-Square DistributionFemaleHealth PersonnelHepatitis BHepatitis CHIV InfectionsHospitals, UrbanHumansInfectious Disease Transmission, Patient-to-ProfessionalLogistic ModelsMaleMiddle AgedNeedlestick InjuriesOccupational ExposurePatient Acceptance of Health CareConceptsHealth care workersAntiretroviral prophylaxisCare workersBlood-borne pathogen exposureSource patient's HIV statusEarly drug discontinuationPatient's HIV statusGastrointestinal side effectsUrban medical centerDrug discontinuationSource patientsHIV statusMedical CenterProphylaxisSerological statusLicensed nursesSide effectsExposure typePathogen exposureJob categoriesExposureMedical studentsStatusDiscontinuationMedications