Hepatic and Gastrointestinal Oxygen and Lactate Metabolism during Low Cardiac Output in Lambs
Fahey J, Lister G, Sanfilippo D, Edelstone D. Hepatic and Gastrointestinal Oxygen and Lactate Metabolism during Low Cardiac Output in Lambs. Pediatric Research 1997, 41: 842-851. PMID: 9167197, DOI: 10.1203/00006450-199706000-00008.Peer-Reviewed Original ResearchConceptsHepatic lactate uptakeHepatic O2 deliveryCardiac outputO2 deliveryHepatic O2 consumptionLactate uptakeLactate accumulationLactic acidosisGI tractNet hepatic lactate uptakeLow cardiac outputGastrointestinal blood flowYoung lambsSystemic O2 deliveryLactate productionExtraction of lactateGreater percent decreaseNet lactate productionO2 consumptionConscious lambsHepatic dysfunctionLactate deliveryO2/minBlood flowAdult subjects