2017
Allogeneic hematopoietic stem cell transplantation is associated with cure and durable remission of late‐onset primary isolated central nervous system hemophagocytic lymphohistiocytosis
Khazal S, Polishchuk V, Soffer G, Prinzing S, Gill J, Mahadeo KM. Allogeneic hematopoietic stem cell transplantation is associated with cure and durable remission of late‐onset primary isolated central nervous system hemophagocytic lymphohistiocytosis. Pediatric Transplantation 2017, 22 PMID: 29239076, DOI: 10.1111/petr.13101.Peer-Reviewed Original ResearchConceptsCNS-HLHDurable remissionsReduced-intensity conditioning regimenHematopoietic stem cell transplantationActive CNS diseaseLate-onset primaryStem cell transplantationAllogeneic HSCTCNS presentationsComorbidity indexConditioning regimenDisease remissionPrompt treatmentHemophagocytic lymphohistiocytosisSignificant morbidityPoor outcomeCell transplantationCNS diseaseAdolescent patientsPRF1 mutationsEarly diagnosisHigh indexRare diseaseRemissionImproved cure
2016
Reduced Intensity Conditioning Followed By Allogeneic Hematopoietic Stem Cell Transplantation Resulted in Cure of a 15 Year Old Male with Primary Isolated CNS Late Onset Familial Hemophagocytic Lymphohistiocytosis
Polishchuk V, Khazal S, Soffer G, Prinzing S, Gill J, Mahadeo K. Reduced Intensity Conditioning Followed By Allogeneic Hematopoietic Stem Cell Transplantation Resulted in Cure of a 15 Year Old Male with Primary Isolated CNS Late Onset Familial Hemophagocytic Lymphohistiocytosis. Transplantation And Cellular Therapy 2016, 22: s347-s348. DOI: 10.1016/j.bbmt.2015.11.840.Peer-Reviewed Original Research