1989
Zwitterionic and Anionic Forms of a Serotonin Analog as Transport Substrates
Rudnick G, Kirk K, Fishkes H, Schuldiner S. Zwitterionic and Anionic Forms of a Serotonin Analog as Transport Substrates. Journal Of Biological Chemistry 1989, 264: 14865-14868. PMID: 2549040, DOI: 10.1016/s0021-9258(18)63781-0.Peer-Reviewed Original ResearchConceptsBiogenic amine transportersAmine transportersPlasma membrane serotonin transporterSubstrate translocationBovine chromaffin granulesTransport substratesHuman blood plateletsSerotonin transportChromaffin granulesTransportersBlood plateletsSerotonin transporterKmIdentical ratesTranslocationSubstrateTransport
1979
Mechanism of imipramine inhibition of platelet 5-hydroxytryptamine transport.
Talvenheimo J, Nelson P, Rudnick G. Mechanism of imipramine inhibition of platelet 5-hydroxytryptamine transport. Journal Of Biological Chemistry 1979, 254: 4631-4635. PMID: 438209, DOI: 10.1016/s0021-9258(17)30057-1.Peer-Reviewed Original Research
1978
Platelet 5-hydroxytryptamine transport, an electroneutral mechanism coupled to potassium.
Rudnick G, Nelson P. Platelet 5-hydroxytryptamine transport, an electroneutral mechanism coupled to potassium. Biochemistry 1978, 17: 4739-42. PMID: 728383, DOI: 10.1021/bi00615a021.Peer-Reviewed Original ResearchConceptsPlasma membrane vesiclesLipophilic cation triphenylmethylphosphoniumMembrane potentialMembrane vesiclesElectroneutral mechanismVesicle membraneIon effluxPorcine blood plateletsAbsence of valinomycinAddition of valinomycinPotassium gradientBlood plateletsValinomycinElectrogenic mechanismMembraneNet influxMechanismDinitrophenolVesiclesTransportLittle effectInfluxTriphenylmethylphosphoniumAbsenceEfflux