2016
Case of a Missed Giant Cell Tumor of Bone: An Opportunity to Observe its Natural History Disease.
Russo GS, Rubio DR, Yacob A, Lindskog DM, Alomari AK, Friedlaender GE. Case of a Missed Giant Cell Tumor of Bone: An Opportunity to Observe its Natural History Disease. Connecticut Medicine 2016, 80: 399-403. PMID: 29782126.Peer-Reviewed Case Reports and Technical NotesConceptsGiant cell tumorAnterior cruciate ligamentCell tumorsIncidental findingRoutine preoperative imagingPre-operative MRIInitial MRIPreoperative imagingSecond MRIMetaphyseal lesionsCruciate ligamentEnlarged massBenign neoplasmsRetrospective evaluationNatural historyTumorsYoung womenHistory diseaseMRIBoneLesionsPainPatientsNeoplasmsHistology
2013
The role of recombinant human platelet-derived growth factor-BB (rhPDGF-BB) in orthopaedic bone repair and regeneration.
Friedlaender GE, Lin S, Solchaga LA, Snel LB, Lynch SE. The role of recombinant human platelet-derived growth factor-BB (rhPDGF-BB) in orthopaedic bone repair and regeneration. Current Pharmaceutical Design 2013, 19: 3384-90. PMID: 23432673, DOI: 10.2174/1381612811319190005.Peer-Reviewed Original ResearchConceptsRecombinant human platelet-derived growth factor-BBClinical studiesMesenchymal stem cellsRecombinant human PDGFStrong mitogenic factorHuman platelet-derived growth factor-BBPlatelet-derived growth factor-BBPivotal clinical studiesImproved safety profileTissue repairGrowth factor-BBMechanism of actionDiabetic patientsChronic footSafety profileAnkle fusionPeriodontal diseaseChronic infectionClinical developmentSoft tissue repairAlveolar boneBone autograftHuman PDGFMitogenic factorFactor-BB